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Updated: Apr 27, 2026

Detecting the Lyme Disease Spirochete, Borrelia Burgdorferi, in Ticks Using Nested PCR
Published on: February 4, 2018
Lyme disease: a review of its epidemiology, evaluation, and treatment
Ted Avi Gerstenblith1, Theodore A Stern2
1Consultation Psychiatry, Massachusetts General Hospital, Boston, MA; Harvard Medical School, Boston, MA.
Background:
Lyme disease, a tick-borne illness transmitted to humans, has become increasingly recognized.
Objective:
Given the myriad neurovegetative and neuropsychiatric symptoms that can be associated with Lyme disease, we sought to review the epidemiology, evaluation, and treatment of the disorder.
Methods:
A case vignette that highlights manifestations of the condition and dilemmas associated with its treatment is presented.
Conclusions:
Knowledge about its symptoms, its abnormal laboratory tests, and its course can help to guide the timely and appropriate management of this spirochetal infection.

