Related Experiment Video
Updated: Apr 27, 2026

09:10
An Immunocompetent Murine Model for Laser Interstitial Thermal Therapy of Glioblastoma
Published on: November 15, 2024
1.1K
[Brenner tumor: one case report and bibliographic review]
Ginecologia Y Obstetricia De Mexico
|July 15, 2014
Summary
Brenner tumor, a rare ovarian neoplasm, is typically benign. This case highlights a benign Brenner tumor identified intraoperatively in a 46-year-old woman with an adnexal mass.
Area of Science:
- Gynecologic Oncology
- Pathology
- Urothelial Neoplasms
Background:
- Brenner tumors are rare ovarian neoplasms, accounting for approximately 1.5% of all ovarian tumors.
- These tumors are characterized by transitional (urothelial) cells arranged in nests within a fibrous stroma.
- They are classified into benign (95%), borderline (3-4%), and malignant (1%) subtypes.
Observation:
- A 46-year-old female patient presented with an adnexal mass.
- Surgical intervention was performed for the adnexal mass.
Findings:
- Intraoperative pathological examination confirmed the presence of a benign Brenner tumor.
- The benign subtype represents the vast majority of Brenner tumors.
Implications:
- Accurate intraoperative diagnosis is crucial for appropriate patient management.
- Understanding the classification and prevalence of Brenner tumors aids in clinical decision-making.
- This case underscores the importance of histopathological confirmation in ovarian mass evaluation.
More Related Videos
Related Concept Videos
Tumor Progression
6.2K
Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
6.2K
The Tumor Microenvironment
6.3K
Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...
6.3K
The Retinoblastoma Gene
3.7K
Tumor suppressor genes are normal genes that can slow down cell division, repair DNA mistakes, or program the cells for apoptosis in case of irreparable damage. Hence, they play an essential role in preventing the proliferation of damaged cells.
The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...
The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...
3.7K

