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Related Concept Videos

Tissue Transplantation01:24

Tissue Transplantation

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Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
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Kidney Transplant II: Surgical Procedure01:26

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Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
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Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

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A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
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Related Experiment Video

Updated: Apr 27, 2026

Procurement for a Vascularized and Reinnervated Abdominal Wall Allotransplantation
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Multivisceral transplantation: where do we stand?

Kalyan Ram Bhamidimarri1, Thiago Beduschi2, Rodrigo Vianna2

  • 1Miami Transplant Institute, University of Miami, 1500 Northwest 12th Avenue, Suite 1101, Miami, FL 33136, USA.

Clinics in Liver Disease
|July 15, 2014
PubMed
Summary

Multivisceral transplantation, including intestinal transplants, is a growing therapy for intestinal failure. Improvements in patient selection, immunosuppression, and perioperative care are enhancing survival rates for these complex procedures.

Keywords:
Intestinal failureIntestinal transplantationLiver transplantationMultivisceral transplantation

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Area of Science:

  • Gastroenterology and Hepatology
  • Transplant Surgery
  • Immunology

Background:

  • Intestinal transplantation is the primary treatment for irreversible intestinal failure.
  • Multivisceral transplantation involves the combined transplant of multiple abdominal organs.
  • There's a notable increase in intestinal and multivisceral transplant volumes and survival rates.

Purpose of the Study:

  • To review key aspects of multivisceral transplantation.
  • To summarize patient selection criteria.
  • To discuss graft types and perioperative management updates.

Main Methods:

  • Literature review of recent advancements in multivisceral transplantation.
  • Analysis of trends in transplant volume and patient outcomes.
  • Synthesis of information on immunosuppression and perioperative care.

Main Results:

  • Significant growth in the number of intestinal and multivisceral transplants performed.
  • Marked improvements in both patient and graft survival.
  • Key factors contributing to improved outcomes include better patient selection, enhanced immunosuppression protocols, and refined perioperative management.

Conclusions:

  • Multivisceral transplantation is an evolving field with improving outcomes.
  • Careful patient selection and optimized management are crucial for success.
  • Continued advancements in immunosuppression and surgical techniques are vital.