Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Radiological Investigation I: X-ray and CT01:30

Radiological Investigation I: X-ray and CT

1.7K
Radiological investigations, including X-rays and computed tomography (CT) scans, are critical for diagnosing and evaluating various medical conditions. These imaging techniques provide valuable insights into the body's internal structures, aiding in the detection of abnormalities, assessment of disease progression, and development of treatment strategies. This article delves into two primary radiological investigations, chest X-rays and CT scans, outlining their purpose, procedures, and...
1.7K
Imaging Studies for Cardiovascular System V: CT01:28

Imaging Studies for Cardiovascular System V: CT

650
Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
650
Imaging Studies III: Computed Tomography01:27

Imaging Studies III: Computed Tomography

887
DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
887
Imaging Studies I: CT and MRI01:14

Imaging Studies I: CT and MRI

1.3K
Introduction: MRI and CT scans are crucial advancements in medical imaging techniques, playing a vital role in diagnosing conditions related to the gastrointestinal (GI) system. Each scan serves distinct purposes, targets specific areas, and requires unique nursing duties.
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
1.3K
Hypersensitivities01:30

Hypersensitivities

7.2K
Hypersensitivity, also known as a hypersensitivity reaction or allergic reaction, is a condition where the body's immune system reacts abnormally to a foreign substance. Such substances, that cause hypersensitivity are referred to as an allergen, could be something typically harmless to most people, like pollen or certain foods.
Types of Hypersensitivities
Hypersensitivity reactions are categorized into four types: Type 1, Type 2, Type 3, and Type 4. Each type has a distinct mechanism...
7.2K
Drug Toxicity: Allergic Reactions01:30

Drug Toxicity: Allergic Reactions

206
Drug-related allergies are immune-mediated responses triggered by the administration of pharmacological agents. These hypersensitivity reactions are classified based on the immune mechanisms involved. The four primary types—Type I, II, III, and IV—are mediated by different immunological pathways and exhibit distinct clinical manifestations.Type I Hypersensitivity/ IgE-Mediated Reactions: Immunoglobulin E (IgE) immediately mediates Type I hypersensitivity reactions. Upon initial...
206

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Outcomes and prognostic factors in patients with systemic mastocytosis and an associated myeloid neoplasm: an international ECNM registry study.

Journal of hematology & oncology·2026
Same author

Resolution of childhood wheat allergy through evolution into WALDA? A case report.

Allergologie select·2026
Same author

Demonstration of Gliadin Penetration into the Epidermis by Tape Stripping as Prerequisite for Percutaneous Sensitisation in Wheat Allergy.

International journal of molecular sciences·2026
Same author

Definition of Competencies for Allergology Specialty/Subspecialty Training in Mast Cell Disorders in Europe: An EAACI Position Paper.

Allergy·2026
Same author

Hypersensitivity to Excipients in Drugs: An EAACI Position Paper.

Allergy·2026
Same author

Casein as rare elicitor of food allergy dependent on augmentation factors - A case report.

Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·2026

Related Experiment Video

Updated: Apr 27, 2026

Anatomical Reconstructions of the Human Cardiac Venous System using Contrast-computed Tomography of Perfusion-fixed Specimens
06:02

Anatomical Reconstructions of the Human Cardiac Venous System using Contrast-computed Tomography of Perfusion-fixed Specimens

Published on: April 18, 2013

11.2K

Hypersensitivity to contrast media and dyes.

Knut Brockow1, Mario Sánchez-Borges2

  • 1Department of Dermatology and Allergy Biederstein, Technische Universität München, Biedersteiner Strasse 29, Munich 80802, Germany.

Immunology and Allergy Clinics of North America
|July 15, 2014
PubMed
Summary

Hypersensitivity reactions to diagnostic contrast media and dyes like iodinated radiocontrast media (RCM) are uncommon but significant. Allergy testing, particularly skin tests, can aid in diagnosing reactions to RCM and other agents.

Keywords:
Blue dyesDiagnostic procedureDyesFluoresceinGadolinium-based contrast mediaHypersensitivityManagementRadiocontrast media

More Related Videos

A Multicenter MRI Protocol for the Evaluation and Quantification of Deep Vein Thrombosis
10:26

A Multicenter MRI Protocol for the Evaluation and Quantification of Deep Vein Thrombosis

Published on: June 2, 2015

17.1K
Basophil Activation Test for Allergy Diagnosis
07:22

Basophil Activation Test for Allergy Diagnosis

Published on: May 31, 2021

9.9K

Related Experiment Videos

Last Updated: Apr 27, 2026

Anatomical Reconstructions of the Human Cardiac Venous System using Contrast-computed Tomography of Perfusion-fixed Specimens
06:02

Anatomical Reconstructions of the Human Cardiac Venous System using Contrast-computed Tomography of Perfusion-fixed Specimens

Published on: April 18, 2013

11.2K
A Multicenter MRI Protocol for the Evaluation and Quantification of Deep Vein Thrombosis
10:26

A Multicenter MRI Protocol for the Evaluation and Quantification of Deep Vein Thrombosis

Published on: June 2, 2015

17.1K
Basophil Activation Test for Allergy Diagnosis
07:22

Basophil Activation Test for Allergy Diagnosis

Published on: May 31, 2021

9.9K

Area of Science:

  • Allergy and Immunology
  • Radiology
  • Pharmacology

Background:

  • Hypersensitivity reactions to diagnostic contrast media and dyes can occur despite their infrequent incidence.
  • The increasing use of these agents means severe reactions are frequently seen in allergy departments.
  • Diagnostic contrast media include iodinated radiocontrast media (RCM), gadolinium-based contrast media, fluorescein, and blue dyes.

Purpose of the Study:

  • To update current knowledge on hypersensitivity reactions to diagnostic contrast media and dyes.
  • To review the evidence for allergologic testing and management for these reactions.
  • To highlight the utility of skin testing in diagnosing hypersensitivity reactions.

Main Methods:

  • Literature review of hypersensitivity reactions to diagnostic contrast media and dyes.
  • Analysis of evidence regarding allergologic testing and management strategies.
  • Evaluation of the role of skin tests in diagnosis.

Main Results:

  • Hypersensitivity reactions to iodinated RCM, gadolinium-based contrast media, fluorescein, and blue dyes are not common but are clinically relevant due to high procedure frequency.
  • Evidence for allergologic testing and management is strongest for iodinated RCM, limited for blue dyes, and insufficient for fluorescein.
  • Skin tests show potential utility in diagnosing hypersensitivity reactions to these compounds.

Conclusions:

  • While uncommon, hypersensitivity reactions to diagnostic contrast media and dyes necessitate careful consideration.
  • Allergologic testing, especially skin testing, is valuable for diagnosing hypersensitivity reactions to iodinated RCM and potentially other agents.
  • Further research is needed to establish robust testing and management guidelines for fluorescein and blue dyes.