Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Longitudinal study on the association between sugar-sweetened beverage intake trajectories and suicide-related behaviors in children].

Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi·2026
Same author

Ultrafast laser-written 3D nano-antenna for flux extraction and vertical focusing above near-infrared waveguides.

Optics express·2026
Same author

[Lingual mucosal graft ureteroplasty for long (≥5 cm) proximal ureteral stricture: a multi-institutional 8-year experience].

Zhonghua wai ke za zhi [Chinese journal of surgery]·2025
Same author

Author Correction: ROBIN: Reference observatory of basins for international hydrological climate change detection.

Scientific data·2025
Same author

Grapevine adopts different strategies in response to drying regimes. Procrastinator or escaper?

Journal of plant physiology·2025
Same author

The effect of pore structure on the erosion resistance of air plasma sprayed thermal barrier coatings on finite element simulation.

Scientific reports·2025

Related Experiment Video

Updated: Apr 27, 2026

Microfluidic Platform with Multiplexed Electronic Detection for Spatial Tracking of Particles
11:54

Microfluidic Platform with Multiplexed Electronic Detection for Spatial Tracking of Particles

Published on: March 13, 2017

8.7K

Multiplexed immunoassay based on micromotors and microscale tags.

D Vilela1, J Orozco, G Cheng

  • 1Department of Nanoengineering, University of California San Diego, La Jolla, California 92093, USA.

Lab on a Chip
|July 15, 2014
PubMed
Summary

This study introduces antibody-micromotors and microwire-tagged proteins for faster immunoassays. This method enables simultaneous detection of multiple biological threats by distinguishing tagged proteins.

More Related Videos

Computer Numerical Control Micromilling of a Microfluidic Acrylic Device with a Staggered Restriction for Magnetic Nanoparticle-Based Immunoassays
09:58

Computer Numerical Control Micromilling of a Microfluidic Acrylic Device with a Staggered Restriction for Magnetic Nanoparticle-Based Immunoassays

Published on: June 23, 2022

1.6K
High-Throughput Automated Multiplex Immunofluorescence Assays for Translational Research
09:12

High-Throughput Automated Multiplex Immunofluorescence Assays for Translational Research

Published on: June 10, 2025

1.4K

Related Experiment Videos

Last Updated: Apr 27, 2026

Microfluidic Platform with Multiplexed Electronic Detection for Spatial Tracking of Particles
11:54

Microfluidic Platform with Multiplexed Electronic Detection for Spatial Tracking of Particles

Published on: March 13, 2017

8.7K
Computer Numerical Control Micromilling of a Microfluidic Acrylic Device with a Staggered Restriction for Magnetic Nanoparticle-Based Immunoassays
09:58

Computer Numerical Control Micromilling of a Microfluidic Acrylic Device with a Staggered Restriction for Magnetic Nanoparticle-Based Immunoassays

Published on: June 23, 2022

1.6K
High-Throughput Automated Multiplex Immunofluorescence Assays for Translational Research
09:12

High-Throughput Automated Multiplex Immunofluorescence Assays for Translational Research

Published on: June 10, 2025

1.4K

Area of Science:

  • Biomedical Engineering
  • Nanotechnology
  • Analytical Chemistry

Background:

  • Immunoassays are crucial for detecting biological agents.
  • Current immunoassays can be slow and lack multiplexing capabilities.
  • Micromotors offer enhanced mixing for faster reactions.

Purpose of the Study:

  • To develop a rapid and multiplexed immunoassay platform.
  • To utilize antibody-functionalized micromotors for accelerated immunoreactions.
  • To enable simultaneous detection of multiple analytes using distinct protein tags.

Main Methods:

  • Coupling antibody-functionalized micromotors with microwire-tagged proteins.
  • Employing micromotor-induced mixing to enhance reaction kinetics.
  • Utilizing size and shape variations of microwire tags for multiplexed discrimination.

Main Results:

  • Achieved accelerated immunoreactions due to micromotor-induced mixing.
  • Demonstrated successful multiplexed discrimination of proteins based on microwire tags.
  • Validated the potential for rapid detection of biological threats.

Conclusions:

  • The developed platform offers a significant advancement in immunoassay speed and multiplexing.
  • This technology holds promise for rapid diagnostics and threat detection.
  • Combining micromotors and tagged particles provides a versatile approach for bioassays.