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[Meningitis after a mouse bite]

Els M L Verhaegh1, Walid Moudrous, Anton G M Buiting

  • 1St. Elisabeth Ziekenhuis, Tilburg.

Nederlands Tijdschrift Voor Geneeskunde
|July 15, 2014
PubMed
Abstract

Insights

Lymphocytic choriomeningitis virus (LCMV) infection, a zoonotic disease from rodents, can cause viral meningitis. In healthy individuals, this LCMV infection is typically self-limiting.

Area of Science:

  • Zoonotic diseases
  • Viral infections
  • Neurovirology

Background:

  • Lymphocytic choriomeningitis virus (LCMV) is a rodent-borne arenavirus causing zoonotic infections.
  • Human LCMV infections are frequently observed during autumn and winter.
  • Transmission occurs via inhalation of aerosols or direct contact with infected rodent excreta.

Observation:

  • A 37-year-old woman presented with severe headache, nausea, and vomiting.
  • The patient reported a mouse bite on her finger three weeks prior.
  • Neurological examination revealed no abnormalities, but cerebrospinal fluid analysis indicated viral meningitis.

Findings:

  • Immunofluorescence serological testing confirmed LCMV infection.
  • The clinical presentation and diagnostic findings were consistent with viral meningitis.

Implications:

  • LCMV infection following rodent contact can lead to viral meningitis.
  • The disease is generally self-limiting in immunocompetent individuals.
  • Highlights the importance of recognizing zoonotic transmission routes for arenaviral infections.

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