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Updated: Apr 27, 2026

Development of Compendium for Esophageal Squamous Cell Carcinoma
Published on: April 12, 2024
MKK6 is upregulated in human esophageal, stomach, and colon cancers
Arif Ali Parray1, Rafia Anjum Baba, Hina Fayaz Bhat
1Department of Biotechnology, University of Kashmir , Srinagar, Jammu and Kashmir , India , 1.
Abstract:
Expression analysis of MKK6 protein in solid tumors has never been investigated. Here, we report systematic analysis of MKK6 protein in different types of human tumor samples using western blotting and immunofluorescence techniques. We observed significant increase in the expression of MKK6 in Esophageal, Stomach, and Colon cancers as compared to controls. Results were alternately confirmed by Immunofluorescence studies. Upregulation of MKK6 protein is indicative of its role in human cancers and could possibly be used as a novel diagnostic or prognostic marker in these cancers.
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