Related Experiment Video
Updated: Apr 27, 2026

Study of Cell Migration in Microfabricated Channels
Published on: February 21, 2014
Giant negative mobility of Janus particles in a corrugated channel
Pulak K Ghosh1, Peter Hänggi2, Fabio Marchesoni3
1Department of Chemistry, Presidency University, Kolkata 700073, India.
Abstract:
We numerically simulate the transport of elliptic Janus particles along narrow two-dimensional channels with reflecting walls. The self-propulsion velocity of the particle is oriented along either its major (prolate) or minor axis (oblate). In smooth channels, we observe long diffusion transients: ballistic for prolate particles and zero diffusion for oblate particles. Placed in a rough channel, prolate particles tend to drift against an applied drive by tumbling over the wall protrusions; for appropriate aspect ratios, the modulus of their negative mobility grows exceedingly large (giant negative mobility). This suggests that a small external drive suffices to efficiently direct self-propulsion of rod-like Janus particles in rough channels.
More Related Videos
Related Concept Videos
Couette Flow
First Law: Particles in Two-dimensional Equilibrium
Newton's first law tells us about...
Protein Diffusion in the Membrane
First Law: Particles in One-dimensional Equilibrium
Negative Regulator Molecules
Behavior of Gas Molecules: Molecular Diffusion, Mean Free Path, and Effusion

