Multiple myeloma presenting as mediastinal mass.
Soumya Panda, Karthik Udupa1, Prasanth Ganesan
1Department of Medical Oncology, Cancer Institute (WIA), Adyar, Chennai, Tamil Nadu, India.
Journal of Cancer Research and Therapeutics
|July 16, 2014
Summary
Extramedullary plasmacytomas (EMP) are rare tumors. This report details two rare cases of mediastinal EMP coexisting with multiple myeloma (MM), highlighting unusual presentations of this plasma cell disorder.
Area of Science:
- Oncology
- Hematology
Background:
- Plasmacytomas are neoplastic plasma cell tumors that can be osseous or non-osseous (extramedullary).
- Extramedullary plasmacytomas (EMP) are uncommon and can be primary or secondary to multiple myeloma (MM).
Observation:
- Mediastinal EMP is an extremely rare presentation.
- Two patients presented with symptomatic mediastinal masses.
Findings:
- Both patients were diagnosed with EMP originating in the mediastinum.
- Both cases demonstrated coexisting multiple myeloma (MM).
Implications:
- Highlights the rare occurrence of mediastinal EMP.
- Underscores the importance of considering unusual presentations of multiple myeloma.
- Emphasizes the need for thorough evaluation of mediastinal masses in the context of plasma cell neoplasms.
