Related Experiment Video
Updated: Apr 27, 2026

State of the Art Cranial Ultrasound Imaging in Neonates
Published on: February 2, 2015
Ultrasound elastography and contrast-enhanced ultrasound in infants, children and adolescents
Martin Stenzel1, Hans-Joachim Mentzel1
1Section Paediatric Radiology, Institute of Diagnostic and Interventional Radiology I, University Hospital Jena, Kochstr. 2, Jena D-07745 Germany.
Insights
Advanced ultrasound techniques like elastography and contrast-enhanced ultrasound offer new ways to assess tissue stiffness and blood flow in children. These methods provide valuable diagnostic information, reducing the need for sedation in pediatric imaging.
Area of Science:
- Pediatric Radiology
- Medical Ultrasound Technology
Background:
- Ultrasound elastography and contrast-enhanced ultrasound are emerging diagnostic tools.
- These advanced techniques offer novel insights beyond traditional imaging.
Purpose of the Study:
- To review the prerequisites, applications, and safety of ultrasound elastography and contrast-enhanced ultrasound in pediatric patients.
- To highlight the diagnostic advantages of these advanced ultrasound modalities.
Main Methods:
- Discussion of the principles, advantages, and limitations of strain elastography, transient elastography, and acoustic radiation force imaging.
- Description of intravesical and intravascular contrast-enhanced ultrasound, including indications and diagnostic utility.
- Presentation of clinical examples for advanced ultrasound techniques in children.
Main Results:
- Latest advancements enable assessment of tissue stiffness and evaluation of blood and urinary flow dynamics.
- Ultrasound now provides functional information on perfusion and flow, complementing morphological data.
- These techniques bridge the information gap compared to cross-sectional imaging requiring sedation.
Conclusions:
- Ultrasound elastography and contrast-enhanced ultrasound enhance diagnostic capabilities in pediatric imaging.
- These methods offer valuable functional information, potentially reducing the need for sedation in young children.
- Advanced ultrasound techniques are becoming indispensable tools in pediatric diagnostics.
Objective:
To describe prerequisites, use, and safety of ultrasound elastography and contrast-enhanced ultrasound in infants, children, and adolescents.
Method:
This review deals with two latest developments in ultrasonography in children. The principle of strain elastography, transient elastography, and acoustic radiation force imaging is discussed, including limitations, and advantages of the different techniques in diagnosing focal and diffuse organ disease. The intravesical (contrast-enhanced voiding ultrasonography) and intravascular use of contrast-media to outline blood, and urinary flow is described, with special emphasis on indications, off-label use, and diagnostic gain. Examples of indications for performing the advanced ultrasound techniques are presented.
Summary And Conclusion:
Latest developments in ultrasound machine engineering, and the availability of contrast-media that interact with ultrasound waves allow for assessment of tissue stiffness/elasticity properties, blood, and urinary flow. Thereby ultrasound is capable not only to depict morphology, but gives the additional information on organ, and focal lesion perfusion, and urinary flow dynamics. The information gap to other cross-sectional techniques such as magnetic resonance imaging, that make potential harmful sedation, and anaesthesia in the youngest children necessary, thereby gets closer.
Related Concept Videos
Ultrasonography
During an ultrasonography procedure, a handheld device called...
Ultrasound II: Endoscopic Ultrasound and FibroScan
Endoscopic Ultrasound (EUS):
Imaging Studies II: Ultrasonography
Imaging Studies for Cardiovascular System II:Types of Echocardiography
Types of Echocardiography
Transthoracic Echocardiography (TTE)
TTE is the most common type of echocardiogram which involves placing a transducer on the patient's chest, emitting sound waves to create heart images. TTE is invaluable for evaluating the heart's size, structure, and motion, making it particularly useful for...
Ultrasound I: Abdominal Ultrasonography
Abdominal ultrasonography, commonly known as abdominal ultrasound, is a vital, non-invasive medical imaging technique widely used in healthcare.
Procedure:
This diagnostic tool allows the clinician to visually inspect internal structures within the abdomen, including vital organs such as the liver, gallbladder, pancreas, kidneys, and spleen.
The abdominal ultrasound process begins with applying a special gel to the patient's skin over the abdomen. This gel enhances the...

