Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

DNA as a Genetic Template

DNA as a Genetic Template

Two structural features of the DNA molecule provide a basis for the mechanisms of heredity: the four nucleotide bases and its double-stranded nature. The Watson-Crick model of double-helical DNA structure, proposed in 1952, drew heavily upon the X-ray crystallography work of researchers Rosalind Franklin and Maurice Wilkins. Watson, Crick, and Wilkins jointly received the Nobel Prize in Physiology or Medicine for their work in 1962. Franklin was, controversially, excluded from the prize for...

DNA as a Genetic Template

DNA as a Genetic Template

From DNA to Protein

From DNA to Protein

The flow of genetic information in cells from DNA to mRNA to protein is described by the central dogma, which states that genes specify the sequence of mRNAs, which in turn specify the sequence of amino acids making up all proteins. The decoding of one molecule to another is performed by specific proteins and RNAs. Because the information stored in DNA is so central to cellular function, it makes intuitive sense that the cell would make mRNA copies of this information for protein synthesis...

Maxam-Gilbert Sequencing

Maxam-Gilbert Sequencing

In the same year as the discovery of the Sanger sequencing method, another group of scientists, Allan Maxam and Walter Gilbert, demonstrated their chemical-cleavage method for DNA sequencing. The Maxam-Gilbert method relies on using different chemicals that can cleave the DNA sequence at specific sites, the separation of resulting DNA fragments of variable size using electrophoresis, and deciphering the DNA sequence from the resulting gel bands.
Challenges of the Maxam-Gilbert Method
The...

The Central Dogma

The Central Dogma

The Central Dogma

The Central Dogma

The central dogma explains the flow of genetic information from DNA nucleotides to the amino acid sequence of proteins.
RNA is the Missing Link Between DNA and Proteins
In the early 1900s, scientists discovered that DNA stores all the information needed for cellular functions and that proteins perform most of these functions. However, the mechanisms of converting genetic information into functional proteins remained unknown for many years. Initially, it was believed that a single gene is...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Fatty acid oxidation-driven migration of PAH4 from rapeseed oil to fume particles during frying.

Food chemistry·2026

Same author

The Efficacy and Safety of Tofacitinib in 48 Children and Adolescents With Alopecia Areata: A Retrospective Study From China.

Pediatric dermatology·2026

Same author

Food-Grade Delivery Systems for Hepatoprotective Functional Foods: From Rational Design and Delivery Mechanisms to Industrial Processing and Nutritional Intervention.

Foods (Basel, Switzerland)·2026

Same author

Case Report: Sufficient pelvic floor muscle function can retain acceptable postoperative defecation function after <i>in-situ</i> anal reconstruction surgery in patients with ultra-low rectal/anal cancer.

Frontiers in surgery·2026

Same author

Systematic toxicokinetic analysis and early hepatic effects evaluation of BbF following acute oral exposure in mice.

Chemico-biological interactions·2026

Same author

Combination therapy with tofacitinib and minoxidil for Bjornstad syndrome caused by novel BCS1L gene variants.

Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·2026

Search research articles

Related Experiment Video

Updated: Apr 27, 2026

DNA-Tethered RNA Polymerase for Programmable In vitro Transcription and Molecular Computation

DNA-Tethered RNA Polymerase for Programmable In vitro Transcription and Molecular Computation

Published on: December 29, 2021

Hiding message into DNA sequence through DNA coding and chaotic maps.

Guoyan Liu¹, Hongjun Liu, Abdurahman Kadir

¹Department of Dermatology, Affiliated Hospital of Weifang Medical University, Weifang, 261031, China.

Medical & Biological Engineering & Computing

|July 16, 2014

Summary

This summary is machine-generated.

This study introduces a robust DNA data hiding method using reversible substitution, enhancing security and capacity. The novel approach improves data embedding in deoxyribonucleic acid sequences.

More Related Videos

Design and Synthesis of a Reconfigurable DNA Accordion Rack

Design and Synthesis of a Reconfigurable DNA Accordion Rack

Published on: August 15, 2018

Self-assembly of Complex Two-dimensional Shapes from Single-stranded DNA Tiles

Self-assembly of Complex Two-dimensional Shapes from Single-stranded DNA Tiles

Published on: May 8, 2015

Related Experiment Videos

Last Updated: Apr 27, 2026

DNA-Tethered RNA Polymerase for Programmable In vitro Transcription and Molecular Computation

DNA-Tethered RNA Polymerase for Programmable In vitro Transcription and Molecular Computation

Published on: December 29, 2021

Design and Synthesis of a Reconfigurable DNA Accordion Rack

Design and Synthesis of a Reconfigurable DNA Accordion Rack

Published on: August 15, 2018

Self-assembly of Complex Two-dimensional Shapes from Single-stranded DNA Tiles

Self-assembly of Complex Two-dimensional Shapes from Single-stranded DNA Tiles

Published on: May 8, 2015

Area of Science:

Bioinformatics
Cryptography
Data Security

Background:

Traditional data hiding methods face limitations in robustness and capacity.
Deoxyribonucleic acid (DNA) sequences offer a unique medium for data embedding due to their high density.
Need for secure and efficient data hiding techniques in biological sequences.

Purpose of the Study:

To propose an improved reversible substitution method for data hiding in DNA sequences.
To enhance the robustness and increase the data hiding capacity of deoxyribonucleic acid-based steganography.
To analyze the key space and hiding capacity of the proposed method.

Main Methods:

Secret message encoding using DNA coding.
Encryption of the encoded message with a pseudo-random sequence.
Generation of hiding locations using a piecewise linear chaotic map.
Embedding the processed message into a randomly selected DNA sequence via the complementary rule.

Main Results:

The proposed method demonstrates enhanced robustness compared to existing techniques.
Significant enlargement of data hiding capacity in deoxyribonucleic acid sequences.
Experimental validation confirms superior performance in terms of robustness and capacity.

Conclusions:

The improved reversible substitution method offers a promising solution for secure DNA data hiding.
The combination of DNA coding, pseudo-random encryption, and chaotic maps effectively boosts performance.
The method provides a secure and high-capacity alternative for steganography in biological data.