Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cognitive Development During Adulthood01:30

Cognitive Development During Adulthood

1.4K
Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
1.4K
Pharmacodynamics in Geriatric Patients: Effects of Age01:27

Pharmacodynamics in Geriatric Patients: Effects of Age

365
Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
365
Peripheral Artery Disease V: Postoperative Nursing Management01:23

Peripheral Artery Disease V: Postoperative Nursing Management

627
During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...
627
Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

392
Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
392
Cardiomyopathy VII: Pre and Post Operative Nursing Management01:28

Cardiomyopathy VII: Pre and Post Operative Nursing Management

457
Patients with hypertrophic cardiomyopathy (HCM) and left ventricular outflow tract (LVOT) obstruction who remain symptomatic despite optimal medical therapy may undergo a septal myectomy (Morrow procedure). This procedure involves excising a portion of the hypertrophied septum below the aortic valve using a heart-lung machine to improve blood flow through the LVOT. Effective preoperative and postoperative nursing management ensures successful patient outcomes, minimizes complications, and...
457
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy01:26

Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy

1.2K
Sigmoidoscopy and laparoscopy are distinct medical procedures that enable physicians to internally inspect different parts of the GI tract. Although they serve different purposes, each is essential for diagnosing and, in some cases, treating various medical conditions.
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
1.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Novel association of <i>NAV3</i> with dilated cardiomyopathy and its role in cardiac fibrosis.

American journal of physiology. Heart and circulatory physiologyยท2026
Same author

Digital Tool-Assisted Hospitalization Detection in the Tailored Antiplatelet Initiation to Lessen Outcomes due to Decreased Clopidogrel Response After Percutaneous Coronary Intervention Study Compared to Traditional Site-Coordinator Ascertainment: Intervention Study.

Journal of medical Internet researchยท2023
Same author

Myocardial Recovery in Recent Onset Dilated Cardiomyopathy: Role of <i>CDCP1</i> and Cardiac Fibrosis.

Circulation researchยท2023
Same author

Safety and Efficacy of CYP2C19 Genotype-Guided Escalation of P2Y<sub>12</sub> Inhibitor Therapy After Percutaneous Coronary Intervention in Chronic Kidney Disease: a Post Hoc Analysis of the TAILOR-PCI Study.

Cardiovascular drugs and therapyยท2022
Same author

Sex-Specific Differences in Clinical Outcomes After Percutaneous Coronary Intervention: Insights from the TAILOR-PCI Trial.

Journal of the American Heart Associationยท2022
Same author

Patient Onboarding and Engagement to Build a Digital Study After Enrollment in a Clinical Trial (TAILOR-PCI Digital Study): Intervention Study.

JMIR formative researchยท2022

Related Experiment Video

Updated: Apr 27, 2026

A Mouse Model of Orthopedic Surgery to Study Postoperative Cognitive Dysfunction and Tissue Regeneration
08:17

A Mouse Model of Orthopedic Surgery to Study Postoperative Cognitive Dysfunction and Tissue Regeneration

Published on: February 27, 2018

19.7K

Post-operative cognitive dysfunction in the elderly: A prospective clinical study.

Nalini Kotekar1, Caroline Sheryl Kuruvilla1, Vishakantha Murthy2

  • 1Department of Anaesthesiology, JSS Medical College, Mysore, Karnataka, India.

Indian Journal of Anaesthesia
|July 16, 2014
PubMed
Summary
This summary is machine-generated.

Post-operative cognitive dysfunction (POCD) affects elderly surgical patients. Female gender and advanced age are significant risk factors for POCD, highlighting the need for targeted preventive strategies.

Keywords:
Anaesthesiacognitive functiondementianeuroprotectionneuropsychological testingpost-operative cognitive dysfunction

Related Experiment Videos

Last Updated: Apr 27, 2026

A Mouse Model of Orthopedic Surgery to Study Postoperative Cognitive Dysfunction and Tissue Regeneration
08:17

A Mouse Model of Orthopedic Surgery to Study Postoperative Cognitive Dysfunction and Tissue Regeneration

Published on: February 27, 2018

19.7K

Area of Science:

  • Geriatric Medicine
  • Anesthesiology
  • Neuroscience

Background:

  • The global aging population necessitates understanding surgical risks in older adults.
  • Post-operative cognitive dysfunction (POCD) is a common, poorly understood complication in the elderly undergoing surgery.
  • Approximately 50% of elderly individuals undergo surgery, making POCD a significant concern.

Purpose of the Study:

  • To assess post-operative cognitive status in elderly patients undergoing non-cardiac surgery.
  • To identify specific cognitive parameters affected by surgery in this demographic.
  • To evaluate risk factors for POCD and explore preventive strategies.

Main Methods:

  • Prospective randomized study of 200 patients aged 60+ undergoing elective non-cardiac surgery.
  • Baseline cognitive assessment 2 days pre-surgery.
  • Post-operative cognitive assessments on days 3, 7, and 30.

Main Results:

  • POCD incidence decreased from day 3 to day 30 post-surgery.
  • Female gender was identified as a significant risk factor for developing POCD.
  • Advancing age and education level were dominant factors; anesthesia type, surgery duration, and comorbidities had no significant influence.

Conclusions:

  • Post-operative cognitive dysfunction (POCD) is a confirmed complication in elderly surgical patients.
  • Female gender and increasing age are key risk factors for POCD.
  • Findings support the development of targeted preventive measures for POCD in the elderly.