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Host modulation therapy: An indispensable part of perioceutics
Minkle Gulati1, Vishal Anand2, Vivek Govila1
1Department of Periodontics, Babu Banarasi Das College of Dental Sciences, Babu Banarasi Das University, Lucknow, India.
Journal of Indian Society of Periodontology
|July 16, 2014
Summary
Periodontitis treatment is evolving beyond antimicrobials to include host-modulating agents. These perioceutics target the host response, complementing antimicrobial therapy for better periodontal health outcomes.
Area of Science:
- Periodontology
- Pharmacology
- Immunology
Background:
- Periodontitis treatment traditionally relies solely on antimicrobials.
- Host immune-inflammatory responses significantly influence periodontal tissue destruction.
- Understanding host-microbial interactions opens avenues for new therapeutic strategies.
Purpose of the Study:
- To review the emerging field of "Perioceutics" for periodontitis management.
- To explore host-modulating agents as adjuncts to traditional antimicrobial therapy.
- To discuss the role of perioceutics in tipping the balance towards periodontal healing.
Main Methods:
- Review of existing literature on host-modulating agents in periodontitis.
- Analysis of systemically delivered perioceutic agents.
- Analysis of locally delivered perioceutic agents.
Main Results:
- Host-modulating agents offer a novel therapeutic approach for periodontitis.
- These agents can be delivered systemically or locally.
- Adjunctive use of host-modulating agents aids in periodontal healing.
Conclusions:
- Perioceutics represents a significant advancement in periodontitis management.
- Targeting host response is crucial for effective periodontal therapy.
- Future research should focus on optimizing perioceutic strategies.
