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Pyelonephritis can be a source of a life-threatening necrotizing myofasciitis

Haytham Kamel1, Mohamed Soliman Edris Edinburgh Awed1, Ahmed Fouad Kotb1

  • 1Department of Urology, Alexandria University, Alexandria, Egypt.

Canadian Urological Association Journal = Journal De L'Association Des Urologues Du Canada
|July 16, 2014
PubMed

Insights

Necrotizing fasciitis is a severe infection of deep fascia. This case report details necrotizing myofasciitis, a rare complication of pyelonephritis in an adult male.

Area of Science:

  • Infectious Diseases
  • Surgical Pathology
  • Internal Medicine

Background:

  • Necrotizing fasciitis is a rapidly progressive, inflammatory infection affecting deep fascia.
  • It can lead to necrosis of skin, subcutaneous tissue, and potentially deeper muscles (necrotizing myositis).
  • This condition requires prompt diagnosis and aggressive management.

Purpose of the Study:

  • To report a rare case of necrotizing myofasciitis secondary to pyelonephritis.
  • To review existing literature on necrotizing infections originating from urinary tract infections.

Main Methods:

  • Case presentation of an adult male with necrotizing myofasciitis.
  • Clinical assessment and diagnostic workup for the source of infection.
  • Literature review of similar cases and pathogenic mechanisms.

Main Results:

  • The patient presented with necrotizing myofasciitis attributed to left-sided pyelonephritis.
  • This highlights a potential, albeit uncommon, pathway for deep soft tissue infections.

Conclusions:

  • Pyelonephritis can serve as a predisposing factor for necrotizing myofasciitis.
  • Early recognition of this association is crucial for timely intervention and improved patient outcomes.
  • Further research may elucidate the specific mechanisms linking urinary infections to deep fascial infections.

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