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Related Concept Videos

Mutations01:35

Mutations

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Mutations are changes in the sequence of DNA. These changes can occur spontaneously or they can be induced by exposure to environmental factors. Mutations can be characterized in a number of different ways: whether and how they alter the amino acid sequence of the protein, whether they occur over a small or large area of DNA, and whether they occur in somatic cells or germline cells.
Chromosomal Alterations Are Large-Scale Mutations
While point mutations are changes in a single nucleotide in...
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Pigmentation01:19

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The color of the skin is influenced by a number of pigments, including melanin, carotene, and hemoglobin. Recall that melanin is produced by cells called melanocytes, which are found scattered throughout the stratum basale of the epidermis. The melanin is transferred to the keratinocytes via melanosomes.
Melanin occurs in two primary forms: eumelanin that provides black and brown pigment and pheomelanin that provides red color. Dark-skinned individuals produce more melanin than those with pale...
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Drug Toxicity: Allergic Reactions01:30

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Drug-related allergies are immune-mediated responses triggered by the administration of pharmacological agents. These hypersensitivity reactions are classified based on the immune mechanisms involved. The four primary types—Type I, II, III, and IV—are mediated by different immunological pathways and exhibit distinct clinical manifestations.Type I Hypersensitivity/ IgE-Mediated Reactions: Immunoglobulin E (IgE) immediately mediates Type I hypersensitivity reactions. Upon initial...
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Photoreceptors and Visual Pathways01:22

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At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...
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Photoreceptors and Plant Responses to Light02:00

Photoreceptors and Plant Responses to Light

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Light plays a significant role in regulating the growth and development of plants. In addition to providing energy for photosynthesis, light provides other important cues to regulate a range of developmental and physiological responses in plants.
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Related Experiment Video

Updated: Apr 27, 2026

Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model
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Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model

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The problems of photosensitivity.

C Hartley-Smith

    The Australian Journal of Physiotherapy
    |July 16, 2014
    PubMed
    Summary

    This study defines photosensitivity and photosensitizers, exploring their mechanisms and management. It details physical therapy interventions like spectrophotometry and filter experiments for managing photosensitive conditions.

    Area of Science:

    • Photochemistry
    • Dermatology
    • Biophysics

    Background:

    • Photosensitivity involves adverse reactions to light.
    • Photosensitizers are substances that increase light sensitivity.
    • Understanding these reactions is crucial for patient management.

    Purpose of the Study:

    • Define photosensitivity and photosensitizers.
    • Elucidate the mechanism of photosensitivity.
    • Discuss management strategies, including physical therapy interventions.

    Main Methods:

    • Literature review to define concepts.
    • Experimental analysis of filters and screens.
    • Spectrophotometry for light analysis.
    • Description of sensitizer and desensitizer properties.

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    Main Results:

    • Detailed definition of photosensitivity and photosensitizers.
    • Explanation of the underlying mechanisms.
    • Evaluation of physical management techniques.

    Conclusions:

    • Photosensitivity requires comprehensive understanding and management.
    • Physical modalities offer viable treatment options.
    • Further research into sensitizers and desensitizers is warranted.