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Related Concept Videos

Degenerative Disc Disease I: Introduction01:27

Degenerative Disc Disease I: Introduction

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Degenerative disc disease is a chronic condition in which intervertebral discs gradually lose structure and function. It is not infectious or autoimmune; rather, it results from age-related biochemical and mechanical changes, influenced by genetic, metabolic, and environmental factors.Structure and Function of DiscsThe spine contains 23 intervertebral discs that absorb load, distribute forces, maintain spacing, and allow flexibility. Each disc consists of a nucleus pulposus, a gel-like core...
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Herniated Intervertebral Disc l: Introduction01:29

Herniated Intervertebral Disc l: Introduction

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Intervertebral disc herniation refers to the displacement of the nucleus pulposus (the gel-like inner core of the disc) through a tear or weakened area in the annulus fibrosus (the outer fibrous ring). The displaced disc material extends beyond the normal boundaries of the disc space and may compress or irritate nearby spinal nerve roots or, less commonly, the spinal cord.Etiology and Risk FactorsHerniation commonly results from degeneration, in which aging reduces disc hydration and...
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Vertebral Column: Regions and Curvature01:16

Vertebral Column: Regions and Curvature

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The vertebral column or spine is a flexible column that supports the head, neck, and body and  allows for their movements. It also protects the spinal cord.
Regions of the Vertebral Column
In an adult, the spine is subdivided into five regions: the cervical, the thoracic, the lumbar, the sacral, and the coccygeal region. The spine initially develops as a series of 33 vertebrae; after 20 years of age, the nine bones in the sacral region, five sacral, and four coccygeal bones fuse to form...
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General Structure of a Vertebra01:30

General Structure of a Vertebra

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A typical vertebra, with the exception of the sacrum and coccyx, consists of a body, a vertebral arch, and seven different projections termed processes. The anterior portion of the vertebrae, the body, supports about half the body’s weight. The vertebral bodies progressively increase in size and thickness from the cervical region to the lumbar region of the vertebral column. The intervertebral discs present between the bodies of adjacent vertebrae firmly unites them, forming a continuous...
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Degenerative Disc Disease ll: Pathophysiology01:23

Degenerative Disc Disease ll: Pathophysiology

21
The symptoms of degenerative disc disease arise from a combination of mechanical compression, vascular compromise, and biochemical inflammation, which together disrupt nerve function and produce pain.Mechanical CompressionDisc degeneration reduces height and elasticity, predisposing to herniation of the nucleus pulposus, a major cause of radicular pain. Herniations may be protrusion (bulging with intact annulus), extrusion (nucleus extends beyond disc but remains connected), or sequestration...
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Related Experiment Video

Updated: Apr 27, 2026

Evaluation of Patients' Posture and Gait Profile After Lumbar Fusion Surgery by Video Rasterstereography and Treadmill Gait Analysis
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The lumbar spine: structure, function, age changes and physiotherapy.

L Twomey, J Taylor

    The Australian Journal of Physiotherapy
    |July 16, 2014
    PubMed
    Summary

    Aging alters lumbar spine structure and function, causing vertebral changes that reduce spinal posture and flexibility. Understanding these age-related lumbar spine changes is crucial for effective physiotherapy interventions.

    Keywords:
    BackacheIntervertebral DiscsLumbar VertebraeSpine

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    Area of Science:

    • Gerontology
    • Orthopedics
    • Biomedical Engineering

    Background:

    • The human lumbar spine undergoes significant structural and functional changes with increasing age.
    • Age-related alterations in vertebral trabeculae impact spinal mechanics and disc health.

    Purpose of the Study:

    • To elucidate the primary structural changes in the aging human lumbar spine.
    • To explain the consequences of these changes on spinal function and load-bearing capacity.

    Main Methods:

    • Analysis of age-related structural changes in lumbar vertebrae, focusing on trabecular bone.
    • Examination of the subsequent effects on intervertebral disc shape and spinal biomechanics.

    Main Results:

    • Selective loss of transversely oriented trabeculae leads to shorter, wider, and more concave vertebral end-plates.
    • Altered disc shape, coupled with biochemical and histological changes, reduces spinal posture, flexibility, and compliance.
    • Diminished capacity of the lumbar spine to withstand sustained loading.

    Conclusions:

    • Age-related structural modifications of the lumbar spine significantly impair its functional capacity.
    • This knowledge is vital for physiotherapists in managing lumbar spinal disorders in aging populations.