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Updated: Apr 27, 2026

Preterm EEG: A Multimodal Neurophysiological Protocol
Published on: February 18, 2012
Sensory and motor development of pre-term infants
1University of Queensland - Brisbane.
Insights
This study tracked 135 preterm infants for 12 months, finding most met age-adjusted milestones. While some showed developmental delays or primitive reflexes, many preterm infants achieved normal motor development.
Area of Science:
- Neonatal development
- Pediatric neurology
- Developmental pediatrics
Background:
- Preterm birth poses risks to infant neurological and developmental outcomes.
- Longitudinal assessment is crucial for understanding the progress of high-risk infants.
- Early identification of developmental trajectories informs intervention strategies.
Purpose of the Study:
- To evaluate the neurological, sensory, motor, and general developmental progress of preterm infants.
- To compare the abilities of age-adjusted preterm infants with standardized developmental scales.
- To identify trends in neurodevelopmental responses and potential delays in preterm infants.
Main Methods:
- A cohort of 135 infants born more than 5 weeks preterm was assessed longitudinally over 12 months.
- Post-term evaluations included a standardized infant ability scale and a graded neurosensory and motor assessment.
- Assessments covered neurological, sensory, motor, and general developmental domains.
Main Results:
- Age-adjusted preterm infants' abilities favorably compared to standardized norms.
- Trends observed in tactile, proprioceptive, vestibular, and eye movement responses.
- Persistence of primitive reflexes and delayed postural reactions noted; motor milestones generally within normal limits.
- Six percent had definite neurological handicaps, 16% showed inconsistent responses, and 11% exhibited developmental delay at 12 months.
Conclusions:
- Most preterm infants achieve age-adjusted developmental milestones within the normal range.
- Specific neurodevelopmental trends, including reflex persistence and postural reaction delays, warrant attention.
- A significant minority of preterm infants require ongoing monitoring for handicaps and developmental delays.
Abstract:
The neurological, sensory, motor and general developmental progress of 135 infants born more than 5 weeks before term was studied. Over a period of 12 months, 122 infants had post-term evaluations at one, four, eight and twelve months. These were carried out using both a standardized infant ability scale and a graded neurosensory and motor assessment. The abilities of the age adjusted pre-term infants compared favourably with the standardized scale of expected age normal abilities. Developmental aspects of tactile, proprioceptive, vestibular and eye movement responses showed some interesting trends. There was some persistence of primitive motor reflexes and an apparent delay in the development of postural reactions. The achievement of the motor milestones such as sitting, crawling, standing and walking did fall within the wide limits of the normal range. Six per cent of the total group had definite neurological handicaps, 16 per cent responded inconsistently during one of the assessments and at 12 months, a further 11 per cent showed evidence of developmental delay.
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