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Epigenetic drugs that do not target enzyme activity

Dafydd R Owen1, John D Trzupek1

  • 1Pfizer Worldwide Research and Development, 200 Cambridgepark Drive, Cambridge, MA 02140, USA.

Drug Discovery Today. Technologies
|July 17, 2014
PubMed
Summary

Epigenetic reader proteins interpret cellular marks without direct enzymatic action. These non-enzymatic proteins are promising drug discovery targets due to their role in transcriptional regulation.

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