Related Experiment Video
Updated: Apr 27, 2026

Use of Ultra-high Field MRI in Small Rodent Models of Polycystic Kidney Disease for In Vivo Phenotyping and Drug Monitoring
Published on: June 23, 2015
Nephrectomy in autosomal dominant polycystic kidney disease: a patient with exceptionally large, still functioning
Edwin M Spithoven1, Niek F Casteleijn1, Paul Berger2
1Department of Nephrology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Abstract:
Autosomal dominant polycystic kidney disease (ADPKD) is the most common hereditary kidney disease. It is characterized by progressive cyst formation in both kidneys, often leading to end-stage kidney disease. Indications for surgical removal of an ADPKD kidney include intractable pain, hematuria, infection, or exceptional enlargement and small abdominal cavity hampering implantation of a donor kidney. We report the case of an extraordinarily large ADPKD kidney weighing 8.7 kg (19.3 lb) with a maximal length of 48 cm (19 inch), and with cysts filled with both clear and bloody fluid.
Related Concept Videos
Nephrons
Kidney Transplant II: Surgical Procedure
Diabetic Nephropathy
Chronic Kidney Disease III: Interprofessional Care
Chronic Kidney Disease I: Introduction
Renal Corpuscle
Glomerulus: Structure and Function
The glomerulus is a tiny, intricate network of capillaries located at the beginning of the nephron. It's enveloped by the Bowman's capsule and receives its blood supply from an afferent arteriole, which divides into numerous...

