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Updated: Apr 26, 2026
Culturing Lymphocytes in Simulated Microgravity Using a Rotary Cell Culture System
Published on: August 25, 2022
Immunomodulatory properties of carbon nanotubes are able to compensate immune function dysregulation caused by
Claudia Crescio1, Marco Orecchioni, Cécilia Ménard-Moyon
1Dipartimento di Scienze Biomediche, Università degli studi di Sassari, 07100 Sassari, Italy.
Abstract:
Spaceflights lead to dysregulation of the immune cell functionality affecting the expression of activation markers and cytokine production. Short oxidized multi-walled carbon nanotubes functionalized by 1,3-dipolar cycloaddition have been reported to activate immune cells. In this Communication we have performed surface marker assays and multiplex ELISA on primary monocytes and T cells under microgravity. We have discovered that carbon nanotubes, through their immunostimulatory properties, are able to fight spaceflight immune system dysregulations.
