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[Vascular calcification in chronic kidney disease]

Yuri Battaglia, Luigi Russo, Gerasimos Asimakopoulos

    Giornale Italiano Di Nefrologia : Organo Ufficiale Della Societa Italiana Di Nefrologia
    |July 18, 2014
    PubMed

    Insights

    Patients with chronic kidney disease (CKD) and end-stage renal disease (ESRD) face higher cardiovascular risks due to traditional and non-traditional factors. Coronary artery calcification (CAC) is a key non-traditional risk, assessed via noninvasive imaging.

    Area of Science:

    • Nephrology and Cardiology
    • Medical Imaging

    Context:

    • Patients with chronic kidney disease (CKD) and end-stage renal disease (ESRD) exhibit elevated cardiovascular (CV) risk compared to the general population.
    • This heightened risk stems from both traditional CV risk factors and unique non-traditional factors associated with renal impairment.

    Purpose:

    • To review the significance of coronary artery calcification (CAC) as a critical non-traditional CV risk factor in CKD and ESRD patients.
    • To discuss the various noninvasive imaging modalities employed for detecting, quantifying, and monitoring CAC progression in this vulnerable population.

    Summary:

    • Coronary artery calcification (CAC) is increasingly recognized as a major non-traditional cardiovascular risk factor in individuals with chronic kidney disease (CKD) or end-stage renal disease (ESRD).
    • Noninvasive imaging techniques provide essential tools for assessing the presence, extent, and progression of CAC, aiding in risk stratification and management.
    • This review highlights the importance of CAC and outlines the commonly utilized noninvasive methods for its evaluation in CKD/ESRD patients.

    Impact:

    • Enhances understanding of cardiovascular disease mechanisms in CKD/ESRD.
    • Informs clinical practice regarding risk assessment and patient monitoring for cardiovascular events.
    • Promotes the use of advanced imaging for better management of CKD/ESRD patients at high cardiovascular risk.

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