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Implantation of Total Artificial Heart in Congenital Heart Disease
Published on: July 18, 2014
Experience with percardiac interventions for multiple congenital heart diseases in children
Shijun Hu1, Yifeng Yang1, Yun Zhu1
1Department of Cardiothoracic Surgery, The Second Xiangya Hospital, Central South University, Changsha, China.
Insights
Percardiac interventions offer a feasible approach for treating children with multiple congenital heart defects, showing satisfactory outcomes. Further research is needed to confirm long-term safety and effectiveness compared to traditional methods.
Area of Science:
- Pediatric Cardiology
- Interventional Cardiology
- Congenital Heart Disease
Background:
- Multiple congenital heart diseases (CHDs) in children often require complex management strategies.
- Minimally invasive techniques are increasingly explored as alternatives to conventional open-heart surgery for CHDs.
Purpose of the Study:
- To evaluate the feasibility and outcomes of percardiac interventions in pediatric patients with multiple CHDs.
- To report initial experience with percardiac device closure and balloon valvuloplasty for various CHD combinations.
Main Methods:
- A cohort of 64 pediatric patients with multiple CHDs underwent attempted percardiac interventions between April 2010 and December 2013.
- Procedures included device closure for ventricular septal defects (VSDs), atrial septal defects (ASDs), patent ductus arteriosus (PDA), and balloon valvuloplasty for pulmonary stenosis (PS).
- Interventions were performed via a mini-incision in the inferior sternum.
Main Results:
- Successful occlusion was achieved in 92% (59/64) of patients; 8% (5/64) required conversion to open-heart surgery.
- A total of 111 devices were implanted (average 1.88 devices/patient) with no severe complications reported.
- Minor complications included incomplete right bundle branch block (8%), transient trivial valve regurgitation (2%), and pericardial effusion (2%).
Conclusions:
- Percardiac intervention is a feasible and satisfactory treatment option for children with multiple CHDs.
- Long-term follow-up and expanded experience are essential to fully assess the safety and efficacy of these minimally invasive procedures.
Objectives:
To report our experience with percardiac interventions for multiple congenital heart diseases in children.
Methods:
From April 2010 to December 2013, a total of 64 patients (33 males and 31 females), aged 4.38 ± 2.97 years, with multiple congenital heart diseases underwent attempted percardiac interventional procedures. The cohort included 34 ventricular septal defects (VSDs) with atrial septal defect (ASD), 9 VSDs with patent foramen ovale (PFO), 17 VSDs with patent ductus arteriosus (PDA), 2 VSDs with pulmonary stenosis (PS) and 2 VSDs with ASD and PDA. A mini-incision in the inferior sternum was made, and percardiac device closure and balloon valvuloplasty were performed for VSD, ASD, PDA and PS.
Results:
Fifty-nine patients (92%) were successfully occluded, and 5 (8%) were converted to open-heart surgery after the failure of occlusion. A total of 111 devices were implanted in the patients (average of 1.88 devices/patient). No severe complications occurred. Incomplete right bundle branch block (IRBBB) occurred in 5 patients (8%) after the operation. Atrioventricular valve regurgitation decreased in 4 patients (6%), but new trivial regurgitation was detected in another patient (2%). A trivial residual shunt without murmur was found in 1 patient (2%), and the residual shunt was closed in the 3-month follow-up. Pericardial effusion occurred in 1 patient (2%).
Conclusions:
Treating the patients who have multiple congenital heart diseases with a percardiac intervention is feasible, and the results should be satisfactory. However, more experience and long-term follow-up are mandatory to assess the safety and effectiveness of these procedures as alternatives to conventional therapy.
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