Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Positron Emission Tomography01:29

Positron Emission Tomography

6.2K
Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body...
6.2K
Imaging Studies II: Positron Emission Tomography and Scintigraphy01:25

Imaging Studies II: Positron Emission Tomography and Scintigraphy

847
Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET
847
Imaging Studies III: Computed Tomography01:27

Imaging Studies III: Computed Tomography

887
DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
887
Computed Tomography01:10

Computed Tomography

7.6K
Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
7.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The role of sacubitril/valsartan in the treatment of chronic heart failure with reduced ejection fraction in hypertensive patients with comorbidities: From clinical trials to real-world settings.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie·2021
Same author

Agreement Between 18F-FDG PET/CT and Whole-Body Magnetic Resonance Compared With Skeletal Survey for Initial Staging and Response at End-of-Treatment Evaluation of Patients With Multiple Myeloma.

Clinical nuclear medicine·2021
Same author

Machine learning-based differentiation between multiple sclerosis and glioma WHO II°-IV° using O-(2-[18F] fluoroethyl)-L-tyrosine positron emission tomography.

Journal of neuro-oncology·2021
Same author

Novel Experience in Hybrid Tracers: Clinical Evaluation of Feasibility and Efficacy in Using ICG-99mTc Nanotop for Sentinel Node Procedure in Breast Cancer Patients.

Clinical nuclear medicine·2020
Same author

Selective internal radiation therapy of hepatic tumors: Morphologic and functional imaging for voxel-based computer-aided dosimetry.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie·2020
Same author

Enhanced antitumor efficacy of lapachol-loaded nanoemulsion in breast cancer tumor model.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie·2020

Related Experiment Video

Updated: Apr 26, 2026

Quantification of Atherosclerotic Plaque Activity and Vascular Inflammation using [18-F] Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography FDG-PET/CT
10:02

Quantification of Atherosclerotic Plaque Activity and Vascular Inflammation using [18-F] Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography FDG-PET/CT

Published on: May 2, 2012

17.0K

¹⁸F-DOPA PET/computed tomography imaging.

Sotirios Chondrogiannis1, Maria Cristina Marzola1, Domenico Rubello1

  • 1Department of Nuclear Medicine, PET/CT Centre, Santa Maria della Misericordia Hospital, Viale Tre Martiri 140, Rovigo 45100, Italy.

PET Clinics
|July 18, 2014
PubMed
Summary
This summary is machine-generated.

18F-DOPA is a PET imaging agent for evaluating neurological conditions and tumors. Understanding its normal distribution and potential pitfalls is crucial for accurate diagnosis.

Keywords:
(18)F-DOPA(18)F-DOPA pitfalls(18)F-DOPA variantsBiodistributionPhysiologic patternl-6-Fluoro-3,4-dihydroxyphenylalanine PET/CT

More Related Videos

Functional Imaging of Brown Fat in Mice with 18F-FDG micro-PET/CT
10:53

Functional Imaging of Brown Fat in Mice with 18F-FDG micro-PET/CT

Published on: November 23, 2012

18.8K
Continuous Blood Sampling in Small Animal Positron Emission Tomography/Computed Tomography Enables the Measurement of the Arterial Input Function
10:21

Continuous Blood Sampling in Small Animal Positron Emission Tomography/Computed Tomography Enables the Measurement of the Arterial Input Function

Published on: August 8, 2019

9.3K

Related Experiment Videos

Last Updated: Apr 26, 2026

Quantification of Atherosclerotic Plaque Activity and Vascular Inflammation using [18-F] Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography FDG-PET/CT
10:02

Quantification of Atherosclerotic Plaque Activity and Vascular Inflammation using [18-F] Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography FDG-PET/CT

Published on: May 2, 2012

17.0K
Functional Imaging of Brown Fat in Mice with 18F-FDG micro-PET/CT
10:53

Functional Imaging of Brown Fat in Mice with 18F-FDG micro-PET/CT

Published on: November 23, 2012

18.8K
Continuous Blood Sampling in Small Animal Positron Emission Tomography/Computed Tomography Enables the Measurement of the Arterial Input Function
10:21

Continuous Blood Sampling in Small Animal Positron Emission Tomography/Computed Tomography Enables the Measurement of the Arterial Input Function

Published on: August 8, 2019

9.3K

Area of Science:

  • Nuclear Medicine
  • Radiopharmaceutical Chemistry
  • Neuroimaging

Background:

  • 18F-DOPA is a radiotracer used in Positron Emission Tomography (PET) imaging.
  • It targets the dopaminergic pathway and has applications in oncology and neurology.
  • Accurate interpretation requires knowledge of normal biodistribution and potential imaging artifacts.

Purpose of the Study:

  • To review the clinical applications of 18F-DOPA PET.
  • To highlight the importance of understanding normal 18F-DOPA distribution and variants.
  • To discuss potential pitfalls, false-positive, and false-negative findings.

Main Methods:

  • Review of existing literature on 18F-DOPA PET imaging.
  • Analysis of biodistribution patterns and physiological variants.
  • Case examples illustrating clinical utility and interpretation challenges.

Main Results:

  • 18F-DOPA PET demonstrates efficacy in assessing dopaminergic pathways, brain tumors, neuroendocrine tumors (NETs), and congenital hyperinsulinism.
  • Normal biodistribution and physiological variants are well-characterized.
  • Potential for false-positive and false-negative results exists in various clinical scenarios.

Conclusions:

  • 18F-DOPA is a valuable radiopharmaceutical with diverse clinical applications.
  • Thorough understanding of its behavior is essential for accurate PET scan interpretation.
  • Awareness of potential interpretation pitfalls improves diagnostic confidence.