[Pathological fractures due to malignant bone tumors]
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Updated: Apr 26, 2026
Modeling Primary Bone Tumors and Bone Metastasis with Solid Tumor Graft Implantation into Bone
Published on: September 9, 2020
M Schultheiss1, S E Traub, A v Baer
1Klinik für Unfall-, Hand-, Plastische- und Wiederherstellungschirurgie, Universitätsklinikum Ulm, Albert-Einstein-Alle 23, 89081, Ulm, Deutschland, markus.schultheiss@uniklinik-ulm.de.
Background:
Malignant bone tumors should be treated within interdisciplinary treatment concepts. The prognosis of pathological fractures is on the whole relatively poor because the fracture is indicative of a large and highly aggressive tumor and the hematoma associated with the fracture could possibly result in spreading of the tumor into the surrounding soft tissues.
Objectives:
This article summarizes the current interdisciplinary treatment concepts under special consideration of pathological fractures in primary bone tumors.
Methods:
A selective literature search was carried out taking own experience into consideration.
Results:
Due to the multimodal therapy approach for osteosarcoma and Ewing's sarcoma, the 5-year survival rate could be increased to 60-70 %.
Conclusion:
The therapeutic treatment should always be carried out within the framework of an interdisciplinary, oncological bone expert team, especially in cases of pathological fractures of malignant bone tumors.
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