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INCLEN Diagnostic Tool for Epilepsy (INDT-EPI) for primary care physicians: development and validation

Ramesh Konanki1, Devendra Mishra, Sheffali Gulati

  • 1Inclen Trust International, New Delhi, India. Correspondence to: Dr Narendra K Arora, Executive Director, The Inclen Trust, International, F1-5, Okhla Industrial Area, Phase-1, New Delhi, India. nkarora@inclentrust.org.

Indian Pediatrics
|July 18, 2014
PubMed

Insights

The INCLEN Diagnostic Tool for Epilepsy (INDT-EPI) accurately identifies children with epilepsy. This validated tool, used by primary care physicians, shows high sensitivity and specificity in diagnosing pediatric epilepsy.

Area of Science:

  • Pediatric Neurology
  • Diagnostic Accuracy
  • Epilepsy Research

Background:

  • Epilepsy diagnosis in children requires specialized expertise.
  • A validated, accessible screening tool is needed for early detection.
  • The INCLEN Diagnostic Tool for Epilepsy (INDT-EPI) was developed to address this need.

Purpose of the Study:

  • To evaluate the diagnostic accuracy of the INDT-EPI.
  • To assess the tool's performance when administered by primary care physicians.
  • To compare the INDT-EPI results against expert pediatric neurologist evaluations.

Main Methods:

  • A diagnostic accuracy study was conducted in tertiary care pediatric centers in India.
  • Children aged 2-9 years were systematically sampled.
  • Evaluations were performed by primary care physicians using the INDT-EPI and by pediatric neurologists (gold standard) in a blinded manner.

Main Results:

  • The study included 240 children with epilepsy and 274 without.
  • The INDT-EPI demonstrated a sensitivity of 85.8% and specificity of 95.3%.
  • Positive and negative predictive values were 94.0% and 88.5%, respectively, with likelihood ratios of 18.25 and 0.15.

Conclusions:

  • The INDT-EPI exhibits high validity for identifying children with epilepsy.
  • The tool is effective when utilized by primary care physicians.
  • This supports the INDT-EPI's role in improving pediatric epilepsy diagnosis.
Abstract

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