Related Experiment Video
Updated: Apr 26, 2026

Author Spotlight: Enhancing Coronary Artery Revascularization
Published on: September 15, 2023
Early and Mid-term Outcomes in Female Patients Undergoing Isolated Conventional Coronary Surgery
Kazim Erguneş1, Levent Yilik1, Ufuk Yetkin1
1Izmir Katip Celebi University Ataturk Training and Research Hospital, Department of Cardiovascular Surgery , Izmir, Turkey.
Insights
Female patients undergoing coronary artery bypass grafting (CABG) had higher in-hospital mortality but similar mid-term survival compared to males. Advanced age, hypertension, diabetes, and hyperlipidemia were key predictors in women.
Area of Science:
- Cardiovascular Surgery
- Cardiac Surgery Outcomes
- Gender Differences in Medicine
Background:
- Observational studies report higher operative mortality in female patients after coronary artery bypass grafting (CABG).
- Conflicting reports exist regarding early mortality differences between female and male CABG patients.
- This study investigates predictors of morbidity, mortality, and survival specifically in female patients undergoing isolated conventional CABG.
Purpose of the Study:
- To identify independent predictive factors for in-hospital mortality and survival in female patients undergoing isolated conventional CABG.
- To compare outcomes, including mortality and survival rates, between female and male patients after CABG.
- To analyze factors influencing in-hospital mortality in both female and male CABG patient cohorts.
Main Methods:
- Retrospective analysis of 1657 patients (361 female, 1296 male) who underwent isolated conventional CABG between January 2002 and December 2009.
- Statistical analysis to identify independent predictive factors for mortality and survival.
- Comparison of in-hospital and mid-term follow-up mortality rates between genders.
Main Results:
- Female patients had significantly higher in-hospital mortality (5.8%) compared to males (3.2%).
- Independent predictors of in-hospital mortality in females included advanced age, hypertension, diabetes, hyperlipidemia, prolonged ventilatory support, and postoperative atrial fibrillation.
- Mid-term survival rates were similar between genders (6.1% vs. 4.6% mortality), with Left Internal Thoracic Artery (LITA) usage being a significant survival predictor in females.
Conclusions:
- Female patients experience higher in-hospital mortality after isolated conventional CABG.
- Despite higher initial mortality, length of ICU/hospital stay and mid-term survival are comparable between genders.
- Predictive factors for mortality and survival differ between female and male CABG patients, highlighting the need for sex-specific considerations.
Introduction:
Several observational studies comparing outcomes between female and male patients after coronary artery bypass grafting (CABG) have shown that operative mortality rate is higher among female patients than in male patients. However, some conflicting studies report that early mortality among female patients is equivalent to that among male patients. We investigated predictive factors of morbidity, mortality and survival in female patients undergoing isolated conventional CABG.
Methods:
Between January 2002 and December 2009, 1657 patients underwent isolated conventional CABG in our clinic. 21.8% (n=361) of patients were female and 78.2% (n=1296) males.
Results:
Advanced age (P<0.0001), hypertension (P<0.0001), diabetes (P<0.0001), and hyperlipidemia (P<0.0001) were the independent predictive factors among female patients. Mean in-hospital mortality rates were 5.8% and 3.2%; for females and males, respectively (P=0.029). Prolonged ventilatory support (P=0.009) and postoperative atrial fibrillation (P=0.049) were the independent predictive factors of in-hospital mortality in female patients. Cardiopulmonary bypass time (P=0.041), prolonged ventilatory support (P<0.0001), and postoperative atrial fibrillation (P=0.031) were the independent predictive factors of in-hospital mortality in male patients. Mean follow-up was 47.51±25.06 months and 48.42±25.21 months among female and male patients (P=0.820). In follow-up, mortality rate was 6.1% (n=22) among female patients and 4.6% (n=60) among male patients (P=0.272). Left internal thoracic artery (LITA) usage (P=0.001) was the independent predictive factor of survival in female patients.
Conclusion:
In-hospital mortality rate was higher in female patients. Length of ICU and hospital stay, and mid-term survival was similar between female and male patients.
More Related Videos
09:12Surgical Swine Model of Chronic Cardiac Ischemia Treated by Off-Pump Coronary Artery Bypass Graft Surgery
Published on: March 27, 2018
09:04Synergizing Antegrade Endoscopic with Bridging Vein Harvesting for Improvement of Great Saphenous Vein Graft Quality from the Lower Leg
Published on: November 19, 2019
Related Concept Videos
Cardiomyopathy VII: Pre and Post Operative Nursing Management
Coronary Artery Disease V: Interprofessional Care
Peripheral Artery Disease V: Postoperative Nursing Management