Early and Mid-term Outcomes in Female Patients Undergoing Isolated Conventional Coronary Surgery

Kazim Erguneş1, Levent Yilik1, Ufuk Yetkin1

  • 1Izmir Katip Celebi University Ataturk Training and Research Hospital, Department of Cardiovascular Surgery , Izmir, Turkey.

Insights

Female patients undergoing coronary artery bypass grafting (CABG) had higher in-hospital mortality but similar mid-term survival compared to males. Advanced age, hypertension, diabetes, and hyperlipidemia were key predictors in women.

Area of Science:

  • Cardiovascular Surgery
  • Cardiac Surgery Outcomes
  • Gender Differences in Medicine

Background:

  • Observational studies report higher operative mortality in female patients after coronary artery bypass grafting (CABG).
  • Conflicting reports exist regarding early mortality differences between female and male CABG patients.
  • This study investigates predictors of morbidity, mortality, and survival specifically in female patients undergoing isolated conventional CABG.

Purpose of the Study:

  • To identify independent predictive factors for in-hospital mortality and survival in female patients undergoing isolated conventional CABG.
  • To compare outcomes, including mortality and survival rates, between female and male patients after CABG.
  • To analyze factors influencing in-hospital mortality in both female and male CABG patient cohorts.

Main Methods:

  • Retrospective analysis of 1657 patients (361 female, 1296 male) who underwent isolated conventional CABG between January 2002 and December 2009.
  • Statistical analysis to identify independent predictive factors for mortality and survival.
  • Comparison of in-hospital and mid-term follow-up mortality rates between genders.

Main Results:

  • Female patients had significantly higher in-hospital mortality (5.8%) compared to males (3.2%).
  • Independent predictors of in-hospital mortality in females included advanced age, hypertension, diabetes, hyperlipidemia, prolonged ventilatory support, and postoperative atrial fibrillation.
  • Mid-term survival rates were similar between genders (6.1% vs. 4.6% mortality), with Left Internal Thoracic Artery (LITA) usage being a significant survival predictor in females.

Conclusions:

  • Female patients experience higher in-hospital mortality after isolated conventional CABG.
  • Despite higher initial mortality, length of ICU/hospital stay and mid-term survival are comparable between genders.
  • Predictive factors for mortality and survival differ between female and male CABG patients, highlighting the need for sex-specific considerations.
Abstract

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