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Oral midazolam for voiding dysfunction in children undergoing voiding cystourethrography: a controlled randomized
Anoush Azarfar1, Mohammad Esmaeeili1, Azadeh Farrokh1
1Department of Pediatric, School of Medicine, Mashhad University of Medical Sciences, Mashhad, IR Iran.
Nephro-Urology Monthly
|July 18, 2014
Summary
Oral midazolam significantly reduced stress and improved cooperation in children undergoing Voiding Cystourethrography (VCUG). This sedative approach is beneficial for pediatric urinary tract infection evaluations.
Area of Science:
- Pediatric Urology
- Clinical Pharmacology
Background:
- Voiding Cystourethrography (VCUG) is the gold standard for diagnosing vesicoureteral reflux.
- VCUG is essential in the workup for pediatric urinary tract infections and voiding dysfunction.
Purpose of the Study:
- To compare the efficacy of oral midazolam versus no sedation for children undergoing VCUG.
- To assess the impact of midazolam on patient comfort and cooperation during the procedure.
Main Methods:
- A randomized clinical trial involving 84 children undergoing VCUG.
- The intervention group received 0.5 mg/kg of oral midazolam 30 minutes prior to the procedure.
- Statistical methods were used to compare outcomes between the midazolam and control groups.
Main Results:
- Urinary tract infections were the primary indication for VCUG in over half of the participants.
- Post-procedure dysuria was more common in girls.
- Children receiving midazolam exhibited significantly less urinary irritation and restlessness one week after the procedure.
Conclusions:
- Oral midazolam at 0.5 mg/kg effectively reduces pediatric patient stress during VCUG.
- Midazolam administration enhances cooperation, improving the overall procedural experience for children.
