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Discovery of a selective, substrate-competitive inhibitor of the lysine methyltransferase SETD8

Anqi Ma1, Wenyu Yu, Fengling Li

  • 1Center for Integrative Chemical Biology and Drug Discovery, Division of Chemical Biology and Medicinal Chemistry, UNC Eshelman School of Pharmacy, ‡Department of Pharmacology, School of Medicine, §Lineberger Comprehensive Cancer Center, and ∥Department of Biochemistry and Biophysics, UNC Macromolecular Interactions Facility, University of North Carolina at Chapel Hill , Chapel Hill, North Carolina 27599, United States.

Journal of Medicinal Chemistry
|July 18, 2014
PubMed

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