Positivity to p-ANCA in patients with status epilepticus
Edoardo Ferlazzo, Antonio Gambardella1, Marina Bellavia
1Department of Medical and Surgical Sciences, Magna Graecia University, Catanzaro, Italy. a.gambardella@unicz.it.
Background:
Status epilepticus (SE) may occur in the setting of several internal or neurologic diseases. Anti-neutrophilic cytoplasmic antibodies (ANCA) are a group of Ig that may be observed in patients with different autoimmune disorders but are particularly associated with systemic vasculitis named ANCA-associated-vasculities (AAV). We herein report 3 patients with SE and positivity to p-ANCA.
Case Presentation:
One patient had a catastrophic evolution and died 5 months after disease onset. The other two patients had a good outcome and remained seizure-free at 30 months and 5 years of follow-up respectively.
Conclusion:
This report highlights the importance of considering ANCA dosage in patients with SE of unclear origin.
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