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Updated: Apr 26, 2026

Preparation of Acute Hippocampal Slices from Rats and Transgenic Mice for the Study of Synaptic Alterations during Aging and Amyloid Pathology
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Preparation of Acute Hippocampal Slices from Rats and Transgenic Mice for the Study of Synaptic Alterations during Aging and Amyloid Pathology

Published on: March 23, 2011

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Perfusion deficits, inflammation and aging precipitate depressive behaviour

Aurel Popa-Wagner1, Ana Maria Buga, Andrei Adrian Tica

  • 1Department of Psychiatry, University of Medicine Rostock, Gehlsheimerstr. 20, 18147, Rostock, Germany, aurel.popa-wagner@med.uni-rostock.de.

Biogerontology
|July 19, 2014
PubMed
Summary

Inflammation and reduced blood flow may explain why some elderly individuals with major depressive disorder (MDD) do not respond to standard treatments. Further research into neuroinflammation could reveal new biomarkers and therapies for depression.

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