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Updated: Apr 26, 2026

Stem Cell-Derived Viral Ag-Specific T Lymphocytes Suppress HBV Replication in Mice
Published on: September 25, 2019
Viral hepatitis and liver transplantation: pathogenesis, prevention and therapy of recurrent disease
Martina Gambato1, Sabela Lens, Carlos Fernández-Carrillo
1Liver Unit, Hospital Clinic, IDIBAPS and CIBEREHD, Barcelona, Spain.
Abstract:
Cirrhosis secondary to hepatitis C virus infection is the leading cause of liver transplantation in most countries. Hepatitis C has an accelerated course after transplantation, and for this reason graft and patient survival are decreased in comparison with other indications of liver transplantation. The development of direct-acting antivirals has been a major step in the management of hepatitis C and in a few years from now the infection will be eradicated with the combination of oral drugs with a good safety profile. This will likely allow prevention of hepatitis C recurrence in most cases. Meanwhile, management of hepatitis C virus infection still relies on the combination of interferon, ribavirin and the first-generation protease inhibitors telaprevir and boceprevir.
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