[McArdle disease or glycogen storage disease type v: Should it affect anaesthetic management?]

Area of Science:

• Metabolic Myopathies
• Clinical Case Reports
• Perioperative Medicine

Background:

• McArdle disease is a rare genetic disorder affecting muscle energy metabolism.
• Patients with McArdle disease are at increased risk for perioperative complications due to impaired glycogenolysis.
• This case highlights the importance of specialized anesthetic and surgical planning for these patients.

Observation:

• A patient with a known history of McArdle disease was scheduled for a mastectomy.
• The case underscores the potential for severe perioperative problems in individuals with this metabolic myopathy.
• Close monitoring and tailored interventions are necessary during the perioperative period.

Findings:

• Understanding the specific physiological challenges of McArdle disease is key to preventing adverse events.
• Proactive management strategies, including appropriate fluid and carbohydrate administration, can mitigate risks.
• Successful surgical outcomes are achievable with meticulous perioperative care.

Implications:

• This case report emphasizes the need for multidisciplinary collaboration in managing patients with McArdle disease.
• Anesthesia and surgical teams should be educated on the specific perioperative risks associated with metabolic myopathies.
• Implementing standardized protocols for McArdle disease patients can improve surgical safety and patient outcomes.