Related Experiment Video
Updated: Apr 26, 2026
Utilization of Ultrasound Guided Tissue-directed Cellular Implantation for the Establishment of Biologically Relevant Metastatic Tumor Xenografts
Published on: May 25, 2018
Primitive neuroectodermal tumor with kidney involvement: a case report
Davood Sharifi Doloui1, Tahereh Fakharian1, Vahid Yahyavi1
1Department of Gastroenterology and Liver Disease, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, Iran.
Abstract:
Primitive neuroectodermal tumor (PNET) is usually an aggressive, rapidly progressing and metastasizing tumor. Occurrence of this type of tumor in the kidney is considered as unusual and few cases have been reported so far. We present a metastatic PNET arising probably from the kidney in a 17-year-old female patient with local invasion and metastasis to the stomach. PNET should be considered as a differential diagnosis of a large heterogeneous soft tissue mass in the abdomen, especially in those with widely local invasion and metastases.
Insights
Metastatic primitive neuroectodermal tumor (PNET) is rare in the kidney. This case highlights PNET as a crucial differential diagnosis for abdominal masses with extensive metastasis.
Area of Science:
- Oncology
- Pathology
Background:
- Primitive neuroectodermal tumors (PNETs) are aggressive neoplasms.
- Renal PNETs are exceptionally rare, with limited documented cases.
Observation:
- A 17-year-old female presented with a large, heterogeneous abdominal soft tissue mass.
- The tumor demonstrated local invasion and metastasis to the stomach.
Findings:
- The patient was diagnosed with a metastatic primitive neuroectodermal tumor originating from the kidney.
- The tumor exhibited aggressive local invasion and distant metastasis.
Implications:
- Primitive neuroectodermal tumor (PNET) must be considered in the differential diagnosis of abdominal masses.
- Early consideration of PNET is vital for patients with extensive local invasion and metastasis.
