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Related Experiment Video

Updated: Apr 26, 2026

Time-lapse Imaging of Mouse Macrophage Chemotaxis

Time-lapse Imaging of Mouse Macrophage Chemotaxis

Published on: April 2, 2020

GI motility: microbiota and macrophages join forces.

Michelle L Robinette¹, Marco Colonna¹

¹Washington University School of Medicine, St. Louis, MO 63110, USA.

|July 19, 2014

Summary

The gut

Area of Science:

Gastroenterology
Neuroimmunology
Microbiology

Background:

Gastrointestinal motility is crucial for digestion, regulated by the enteric nervous system.
The gut's complex functions involve smooth muscle contractions and neural control.

Purpose of the Study:

To investigate the regulatory mechanisms of gastrointestinal motility.
To explore the interplay between the enteric nervous system, immune system, and gut microbiota.

Main Methods:

The study involved analyzing the interactions between the enteric nervous system, immune system, and gut microbiota.
Research focused on the physiological regulation of gut functions.

Main Results:

Muller et al. discovered that the immune system and gut microbiota significantly influence gastrointestinal motility.

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Last Updated: Apr 26, 2026

Time-lapse Imaging of Mouse Macrophage Chemotaxis

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Depletion and Reconstitution of Macrophages in Mice

Depletion and Reconstitution of Macrophages in Mice

Published on: August 1, 2012

An Intestinal Gut Organ Culture System for Analyzing Host-Microbiota Interactions

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This interaction adds a new regulatory layer to digestive processes.

Conclusions:

The gut's regulatory network for motility is more complex than previously understood.
Integrating immune and microbial factors is key to understanding digestive health.