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Managing 'resistance': is adherence a target for treatment?
1Service of Nephrology and Hypertension, Department of Medicine, CHUV, Lausanne, Switzerland.
Current Opinion in Nephrology and Hypertension
|July 19, 2014
Summary
Low adherence to medication significantly impacts resistant hypertension management, affecting up to 50% of patients. Improving drug adherence is crucial for better blood pressure control, especially with limited new hypertension medications available.
Area of Science:
- Cardiology
- Pharmacology
- Internal Medicine
Background:
- Adherence to preventive measures and medications is vital for hypertension management.
- This is especially critical in resistant hypertension cases where treatments yield suboptimal results.
Purpose of the Study:
- To review recent findings on drug adherence in patients with resistant hypertension.
- To highlight the underappreciated role of adherence in treatment resistance.
Main Methods:
- Literature review of recent observations on drug adherence in resistant hypertension.
- Analysis of studies reporting the prevalence and impact of low adherence.
Main Results:
- Low adherence to prescribed medications affects up to 50% of patients with resistant hypertension.
- Good adherence is linked to improved prognosis, but should be interpreted alongside clinical outcomes.
- Reliable adherence data can aid physicians in managing apparent treatment resistance.
Conclusions:
- Focusing on adherence to existing hypertension drugs is key to improving population blood pressure control, given slow new drug development.
- Increased emphasis on measuring drug adherence in resistant hypertension is recommended to prevent unnecessary investigations and treatments.
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