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Updated: Apr 26, 2026

Digital PCR for Quantifying Circulating MicroRNAs in Acute Myocardial Infarction and Cardiovascular Disease
Published on: July 3, 2018
A study of cardiovascular miRNA biomarkers for Kawasaki disease
Anne H Rowley1, Adam J Pink, Rebecca Reindel
1From the *Department of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, IL; †Department of Microbiology/Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL; ¶Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL; ‡Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL; and §Department of Microbiology/Immunology, Loyola University Stritch School of Medicine, Maywood, IL.
Abstract:
We hypothesized that cardiovascular miRNAs might be diagnostic biomarkers for Kawasaki disease (KD). We identified dysregulated miRNAs in KD coronary arteries, and tested sera from KD patients and febrile controls for cardiovascular miRNAs using 2 methods. We did not identify cardiovascular miRNAs diagnostic for KD; our results may help guide future studies of potential miRNA biomarkers for KD.
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