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Related Concept Videos

Radiological Investigation III: Pulmonary Angiogram and PET Scan01:13

Radiological Investigation III: Pulmonary Angiogram and PET Scan

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Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
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Related Experiment Video

Updated: Apr 26, 2026

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
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Postmastectomy radiotherapy: indications and implications.

S M Walsh1, A J Lowery1, R S Prichard1

  • 1Department of Breast Surgery, St. Vincent's University Hospital, Elm Park, Dublin 4, Ireland.

The Surgeon : Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland
|July 20, 2014
PubMed
Summary
This summary is machine-generated.

Postmastectomy radiotherapy (PMRT) is crucial for high-risk breast cancer patients but can affect breast reconstruction outcomes. Careful patient counseling is essential before immediate reconstruction if PMRT is likely needed.

Keywords:
Breast reconstructionMastectomyPostmastectomy radiotherapy

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Area of Science:

  • Oncology
  • Surgical Oncology
  • Radiation Oncology

Background:

  • Mastectomy is required for about one-third of breast cancer patients.
  • Immediate reconstruction is often offered to these patients.
  • Postmastectomy radiotherapy (PMRT) can have side effects on reconstructed breasts.

Purpose of the Study:

  • Review issues surrounding PMRT.
  • Discuss patient selection for PMRT.
  • Analyze the effect of PMRT on reconstructive decisions.

Main Methods:

  • Literature review conducted.
  • Medline database utilized.

Main Results:

  • PMRT is indicated for high risk of loco-regional recurrence.
  • PMRT strongly recommended for >=4 positive lymph nodes; other indications debated.
  • Immediate reconstruction generally has favorable outcomes, but PMRT may necessitate revision surgery.

Conclusions:

  • Careful patient counseling is vital before immediate reconstruction when PMRT is anticipated.
  • Evidence largely from retrospective studies; few randomized trials exist.
  • PMRT's impact on breast reconstruction requires careful consideration.