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Updated: Apr 26, 2026

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement
Published on: December 11, 2017
Replacement of the aortic root with a composite valve-graft conduit: risk factor analysis in 246 consecutive patients
Kei Woldendorp1, Eric Starra2, Michael Seco3
1University of New South Wales Medical School, Sydney, Australia; The Baird Institute of Applied Heart and Lung Surgical Research, Sydney, Australia.
Insights
Composite valve-graft (CVG) aortic root replacement is a safe procedure with low mortality rates, comparable to international studies. This study highlights its effectiveness in an Australian setting for various aortic conditions.
Area of Science:
- Cardiovascular Surgery
- Thoracic Surgery
- Aortic Surgery
Background:
- Composite valve-graft (CVG) aortic root replacement is a recognized treatment for aortic root conditions.
- Few large-scale studies have evaluated this procedure in Australia.
Purpose of the Study:
- To assess the outcomes of CVG aortic root replacement in an Australian cohort.
- To identify predictors of mortality for this procedure.
Main Methods:
- A retrospective review of 246 patients undergoing CVG root replacement between January 2006 and June 2013.
- Analysis of patient demographics, indications for surgery, and 30-day mortality.
- Multivariate analysis to identify significant predictors of mortality.
Main Results:
- The overall 30-day mortality was 5.7% (elective 2.2%, emergent 17.2%).
- Significant predictors of 30-day mortality included acute aortic dissection, peripheral vascular disease, new ventricular tachycardia, re-operation for bleeding, mitral stenosis, and cerebrovascular accident.
Conclusions:
- The 30-day mortality in this Australian series is comparable to international studies.
- CVG aortic root replacement can be performed with low risk in experienced centers.
Background:
Composite valve-graft (CVG) replacement of the aortic root is a well-studied and recognised treatment for various aortic root conditions, including valvular disease with associated aortopathy. There have been few previous studies of the procedure in large numbers in an Australian setting.
Method:
From January 2006 to June 2013, 246 successive patients underwent CVG root replacements at our institution. Mean age was 56.8 years, 85.4% were male, and 87 had evidence of bicuspid aortic valve. Indications for operation included ascending aortic aneurysm in 222 patients, annuloaortic ectasia in 67 patients, and aortic dissection in 38 patients.
Results:
The overall unit 30-day mortality was 5.7%, including: elective 30-day mortality of 2.2%, and emergent 30-day mortality of 17.2%. Statistically significant multivariate predictors of 30-day mortality were: acute aortic dissection (OR=20.07), peripheral vascular disease (OR=11.17), new ventricular tachycardia (OR=30.17), re-operation for bleeding (OR=14.42), concomitant mitral stenosis (OR=68.30), and cerebrovascular accident (OR=144.85).
Conclusions:
Low postoperative mortality in our series matches closely with results from similar sized international studies, demonstrating that this procedure can be performed with low risk in centres with sufficient experience in the operative procedure.
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