Replacement of the aortic root with a composite valve-graft conduit: risk factor analysis in 246 consecutive patients

Kei Woldendorp1, Eric Starra2, Michael Seco3

  • 1University of New South Wales Medical School, Sydney, Australia; The Baird Institute of Applied Heart and Lung Surgical Research, Sydney, Australia.

Insights

Composite valve-graft (CVG) aortic root replacement is a safe procedure with low mortality rates, comparable to international studies. This study highlights its effectiveness in an Australian setting for various aortic conditions.

Area of Science:

  • Cardiovascular Surgery
  • Thoracic Surgery
  • Aortic Surgery

Background:

  • Composite valve-graft (CVG) aortic root replacement is a recognized treatment for aortic root conditions.
  • Few large-scale studies have evaluated this procedure in Australia.

Purpose of the Study:

  • To assess the outcomes of CVG aortic root replacement in an Australian cohort.
  • To identify predictors of mortality for this procedure.

Main Methods:

  • A retrospective review of 246 patients undergoing CVG root replacement between January 2006 and June 2013.
  • Analysis of patient demographics, indications for surgery, and 30-day mortality.
  • Multivariate analysis to identify significant predictors of mortality.

Main Results:

  • The overall 30-day mortality was 5.7% (elective 2.2%, emergent 17.2%).
  • Significant predictors of 30-day mortality included acute aortic dissection, peripheral vascular disease, new ventricular tachycardia, re-operation for bleeding, mitral stenosis, and cerebrovascular accident.

Conclusions:

  • The 30-day mortality in this Australian series is comparable to international studies.
  • CVG aortic root replacement can be performed with low risk in experienced centers.
Abstract

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