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Author Spotlight: Assessing Ischemic Stroke Damage Through Middle Cerebral Artery Occlusion Model
Published on: August 11, 2023
Risk factors and imaging characteristics of childhood stroke in china
Yaxian Deng1, Yilong Wang2, Weili Yang1
1Department of Pediatrics, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Insights
Childhood stroke is more prevalent in Chinese boys, with moyamoya disease and arteriovenous malformations being leading causes. Hemorrhagic stroke occurred more frequently than ischemic stroke in this population.
Area of Science:
- Neurology
- Pediatrics
- Epidemiology
Background:
- Childhood stroke reports from China are limited.
- Understanding the clinical spectrum, risk factors, and imaging is crucial for pediatric stroke management.
Purpose of the Study:
- To describe the clinical characteristics, risk factors, and imaging findings of childhood stroke in China.
- To analyze the prevalence and causes of ischemic and hemorrhagic stroke in children.
Main Methods:
- Retrospective analysis of a hospital discharge database from 2002 to 2011.
- Inclusion of 478 first admissions for childhood stroke.
- Categorization into ischemic stroke (229 cases) and hemorrhagic stroke (249 cases).
Main Results:
- Boys constituted over 60% of all stroke types.
- Moyamoya disease led ischemic stroke; arteriovenous malformations led hemorrhagic stroke.
- Hemiplegia and headache were the most common symptoms; arteriopathy was the primary cause.
Conclusions:
- Hemorrhagic stroke was more prevalent than ischemic stroke in Chinese children.
- Arteriopathy is the most common cause of childhood stroke, consistent with Western data.
- Further research is needed to address the scarcity of childhood stroke data from China.
Abstract:
There are scarce reports of childhood stroke from China. Our objective was to describe the clinical spectrum, risk factors, and imaging characteristics of childhood stroke in China. Using a hospital discharge database, children with stroke who were first admitted from 2002 to 2011 were retrospectively enrolled. We identified 478 first admissions with childhood stroke, including 229 cases of ischemic stroke and 249 hemorrhagic stroke. Boys accounted for more than 60% in all stroke types (62.2% for ischemic stroke, intracerebral hemorrhage for 66.2%). The leading cause was moyamoya for ischemic stroke and arteriovenous malformations for intracerebral hemorrhage. Hemiplegia and headache were the most common presenting features. Internal carotid artery and middle cerebral artery were the most involved arteries according to imaging examination in the ischemic stroke. A total of 8 patients died of intracerebral hemorrhage. The prevalence of hemorrhagic stroke was more than that of ischemic stroke. As Western countries, arteriopathy was the most common cause of childhood stroke.
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