A very unusual organism causing stroke-like symptoms
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Updated: Apr 26, 2026

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Published on: May 24, 2021
Eve McCann1, Mark Barber1, Pamela Hunter2
1Medicine for the Elderly, Monklands Hospital, Lanarkshire, UK.
Abstract:
A 78-year-old man presented to hospital with new onset confusion and fever. The working diagnosis was of delirium due to an infection of unknown source, and empirical i.v. antibiotic treatment was given. Two days later, he deteriorated and developed clinical features in keeping with a total anterior circulation stroke. Brain imaging was unremarkable. Blood cultures grew an organism subsequently identified as Facklamia languida. Following treatment with broad-spectrum antibiotics, his condition improved. A diagnosis of F. languida septicaemia, leading to presumed (unwitnessed) seizure and Todd's paresis was made. The patient went on to make a full recovery and was discharged home. Stroke mimics are common and may be eminently treatable. Around a quarter of patients initially suspected to have a stroke are subsequently found to have an alternative diagnosis.
Insights
A rare Facklamia languida infection caused stroke-like symptoms in an elderly man. Prompt antibiotic treatment led to a full recovery, highlighting the importance of considering treatable infections as stroke mimics.
Area of Science:
- Infectious Diseases
- Neurology
- Internal Medicine
Background:
- Delirium and fever are common presenting symptoms in elderly patients.
- Stroke is a leading cause of morbidity and mortality, necessitating rapid diagnosis and treatment.
Observation:
- An elderly male presented with confusion and fever, initially suspected as delirium due to infection.
- The patient's condition worsened, exhibiting symptoms consistent with a total anterior circulation stroke.
- Brain imaging was unremarkable, prompting further investigation into the cause of neurological deterioration.
Findings:
- Blood cultures revealed Facklamia languida, a rare bacterial pathogen.
- The patient was diagnosed with Facklamia languida septicemia.
- Neurological symptoms resolved following broad-spectrum antibiotic treatment, suggesting a diagnosis of seizure and Todd's paresis secondary to infection.
Implications:
- Facklamia languida septicemia can present as a stroke mimic.
- Infectious etiologies should be considered in patients presenting with acute neurological deficits.
- Early identification and treatment of infections can lead to complete recovery and prevent misdiagnosis of stroke.
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Transient Ischemic Attack l: Introduction
Stroke: Introduction and Types
Hemorrhagic Stroke l: Introduction
Ischemic Stroke l: Introduction
Ischemic Stroke ll: Pathophysiology
Hemorrhagic Stroke ll: Pathophysiology

