Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Changed thyroid function parameters in severe extrathyroidal diseases].

F Herrmann1

  • 1Poliklinischen Abteilung, Karl-Marx-Universität Leipzig.

Zeitschrift Fur Die Gesamte Innere Medizin Und Ihre Grenzgebiete
|June 15, 1989
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Antibiotic prescription for older patients in end-of-life care: a randomized survey among physicians in Switzerland.

BMC geriatrics·2026
Same author

Measurements of Chemical Potentials in Pb-Pb Collisions at sqrt[s_{NN}]=5.02  TeV.

Physical review letters·2024
Same author

Observation of Medium-Induced Yield Enhancement and Acoplanarity Broadening of Low-p_{T} Jets from Measurements in pp and Central Pb-Pb Collisions at sqrt[s_{NN}]=5.02  TeV.

Physical review letters·2024
Same author

Photoproduction of K^{+}K^{-} Pairs in Ultraperipheral Collisions.

Physical review letters·2024
Same author

Emergence of Long-Range Angular Correlations in Low-Multiplicity Proton-Proton Collisions.

Physical review letters·2024
Same author

First Measurement of the |t| Dependence of Incoherent J/ψ Photonuclear Production.

Physical review letters·2024
Same journal

[Report on the Fifth International Congress on Blood Transfusion, Paris, 13 to 19 September 1954].

Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete·2014
Same journal

[Blood coagulation; literature from 1952 to 1954. VI].

Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete·2014
Same journal

[Blood coagulation; publications from 1952-1954. V].

Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete·2014
Same journal

[Blood coagulation from 1952-1954. IV].

Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete·2014
Same journal

[Report on the fourth congress of the European Gastroenterological Society in Paris, 27 June to 2 July 1954].

Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete·2014
Same journal

[The islands of Langerhans in pancreatic carcinoma].

Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete·2014
See all related articles

Patients with critical non-thyroidal illnesses (NTI) can experience low thyroid hormone levels, but this is an adaptive response, not true hypothyroidism. Thyroid hormone replacement is generally not recommended for these patients.

Area of Science:

  • Endocrinology
  • Internal Medicine

Context:

  • Critical illnesses, including severe liver/kidney disease, inflammation, and metabolic disorders, frequently impact thyroid hormone levels.
  • The non-thyroidal illness (NTI) syndrome is characterized by altered thyroid hormone concentrations, particularly decreased triiodothyronine (T3) and thyroxine (T4).

Purpose:

  • To investigate the clinical significance and implications of altered thyroid hormone levels in patients with critical non-thyroidal illnesses.
  • To differentiate between adaptive hormonal changes and true thyroid dysfunction in critically ill patients.

Summary:

  • Critically ill patients often present with low serum T3 and T4 levels, termed low T3-syndrome or low T3-low T4-syndrome.
  • Despite reduced thyroid hormone levels and potential pituitary regulation issues, these patients typically remain clinically euthyroid, indicating an adaptive response rather than hypothyroidism.

Related Experiment Videos

  • A significant decrease in serum T4 is associated with a poor prognosis.

    • Impact:

    • This study suggests that thyroid hormone substitution is not indicated in NTI syndrome, as the hormonal changes are adaptive.
    • Accurate diagnosis of thyroid dysfunction in NTI can be challenging; however, utilizing sensitive TSH assays may improve diagnostic accuracy.