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Behçet's disease, echocardiographers, and cardiac surgeons: together is better
1Lecturer of Cardiovascular Medicine, Cairo University Hospital, Cairo, Egypt.
Insights
Behçet's disease, an inflammatory condition, can cause serious cardiac complications like aortic dilation and aneurysms. Early diagnosis and specialized management are crucial to prevent surgical failure and improve patient outcomes.
Area of Science:
- Cardiology
- Rheumatology
- Internal Medicine
Background:
- Behçet's disease is a rare inflammatory disorder with unknown causes.
- It is characterized by recurrent oral and genital ulcers, uveitis, and skin lesions.
- Cardiac abnormalities, including aortic root dilation, valve regurgitation, thrombi, and pulmonary artery aneurysms, are recognized complications.
Purpose of the Study:
- To review the major cardiac complications associated with Behçet's disease.
- To highlight the importance of recognizing these complications for surgical management.
- To discuss the challenges and specific treatment strategies required for these patients.
Main Methods:
- This is a review article.
- It synthesizes existing literature on cardiac manifestations in Behçet's disease.
- Focuses on complications requiring surgical intervention.
Main Results:
- Cardiac complications such as aortic root dilation, aortic valve regurgitation, intracardiac thrombi, and pulmonary artery aneurysms can occur.
- These findings may appear before other disease symptoms and necessitate surgery.
- Missed diagnosis of Behçet's disease pre-surgery is linked to increased surgical failure, recurrence, and mortality.
Conclusions:
- Cardiac complications are significant in Behçet's disease and require specialized management.
- Timely diagnosis of Behçet's disease is critical for successful surgical intervention.
- Adherence to specific treatment strategies is essential to mitigate risks in patients with Behçet's disease.
Abstract:
Behçet's disease is an inflammatory disorder of unknown etiology, characterized by recurrent oral aphthous ulcers, genital ulcers, uveitis, and skin lesions. Many abnormal echocardiographic findings have been previously reported in patients with Behçet's disease. Some of these; namely, aortic root dilation, aortic valve regurgitation, intracardiac thrombi, and pulmonary artery aneurysm may precede other manifestations of the disease and occasionally require surgical intervention for proper management. Compared to patients without Behçet's disease, management of these complications in patients with the disease is challenging and requires different treatment strategies. If diagnosis of Behçet's disease is missed prior to surgical intervention, higher incidence of surgical failure, recurrence, and even higher postoperative mortality may occur. In this review, the author discusses these major cardiac complications of Behçet's disease.
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