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HPLC-based Assay to Monitor Extracellular Nucleotide/Nucleoside Metabolism in Human Chronic Lymphocytic Leukemia Cells
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Eltrombopag for resistant immune thrombocytopenia secondary to chronic lymphocytic leukaemia
1Wellington Blood and Cancer Centre, Capital and Coast District Health Board, Wellington, New Zealand.
Internal Medicine Journal
|July 22, 2014
Abstract:
Autoimmune manifestations are a common occurrence with chronic lymphocytic leukaemia (CLL). We describe a case of CLL-associated immune thrombocytopenia (ITP) that had a loss of response to standard treatment for ITP. The thrombopoeitin receptor agonist, eltrombopag, was successfully used preoperatively to increase the platelet count to a safer level, in this instance to facilitate laparoscopic splenectomy.

