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Published on: July 11, 2019
Percutaneous transluminal angioplasty for central venous disease in dialysis patients: influence on cardiac function
Masataka Banshodani1, Hideki Kawanishi, Sadanori Shintaku
11 Department of Artificial Organs, Akane-Foundation, Tsuchiya General Hospital 3-30, Nakajimacho, Naka-ku, Hiroshima - Japan.
Insights
Percutaneous transluminal angioplasty (PTA) for central venous disease (CVD) in hemodialysis patients increases vascular access flow but does not affect cardiac function. This study evaluated cardiac function, etiology, and treatment in these patients.
Area of Science:
- Nephrology
- Cardiology
- Vascular Surgery
Background:
- Central venous disease (CVD) is a common complication in hemodialysis (HD) patients, often leading to impaired vascular access.
- Increased vascular access flow post-percutaneous transluminal angioplasty (PTA) may impact cardiac function in HD patients.
Purpose of the Study:
- To evaluate cardiac function, etiology, and treatment outcomes in hemodialysis patients with central venous disease (CVD).
- To assess the relationship between increased vascular access flow after PTA and cardiac function in HD patients.
Main Methods:
- Retrospective study of 26 hemodialysis patients with CVD treated with PTA between June 2006 and February 2013.
- Analysis of vascular access types, CVD locations, computed tomography findings, PTA success rates, and patency rates.
- Evaluation of cardiac function parameters including left ventricular ejection fraction and inferior vena cava diameter pre- and post-PTA.
Main Results:
- PTA success rate was 96%, with primary patency rates at 12 months of 57%.
- Brachial artery flow volume significantly increased post-PTA (1306 vs. 957 ml/min; p=0.005).
- No significant changes were observed in left ventricular ejection fraction (57% vs. 60%; p=0.2) or inferior vena cava diameter (17 vs. 17 mm; p=0.9) post-PTA.
Conclusions:
- Increased vascular access flow following PTA for CVD in hemodialysis patients is not associated with adverse effects on cardiac function.
- PTA is an effective treatment for central venous disease, improving vascular access flow without compromising cardiac status.
Purpose:
Increased vascular access flow after percutaneous transluminal angioplasty (PTA) for central venous stenosis and occlusion (central venous disease, CVD) can affect cardiac function in hemodialysis (HD) patients. We evaluated the cardiac function, etiology, and treatment in HD patients with CVD.
Methods:
HD patients with CVD treated by PTA between June 2006 and February 2013 were studied.
Results:
Of the 26 patients, 22 had left arteriovenous fistulas (AVFs), 1 left arteriovenous graft (AVG), 2 right AVFs, and 1 right AVG. CVD sites were the left brachiocephalic vein (LBCV; n=13), left subclavian vein (LSCV; n=7), both LBCV and LSCV (n=3), right BCV (n=2), and right SCV (n=1). Computed tomography findings indicated a high extrinsic compression rate for the LBCV (91%) and LSCV (50%). The success rate of PTA was 96%. The primary patency rates at 3, 6, 9, and 12 months were 81%, 73%, 65%, and 57%, respectively. The post-PTA brachial artery flow volume was significantly increased compared with the pre-PTA volume (1306 vs. 957 ml/min; p=0.005). The post-PTA left ventricular ejection fraction and expiration inferior vena cava diameter were the same as the pre-PTA values (57% versus 60%, p=0.2 and 17 versus 17 mm, p=0.9, respectively).
Conclusions:
Our findings suggest that increased vascular access flow after PTA for CVD has no relation to cardiac function.
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