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Updated: Mar 1, 2026

Defining Gene Functions in Tumorigenesis by Ex vivo Ablation of Floxed Alleles in Malignant Peripheral Nerve Sheath Tumor Cells
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Genomic medicine and targeted therapy for solid tumors

Emily A Stevens1, Cristina P Rodriguez

  • 1Seattle Cancer Care Alliance, University of Washington, Seattle, Washington; Fred Hutchinson Cancer Research Center, University of Washington, Seattle, Washington.

Journal of Surgical Oncology
|July 22, 2014
PubMed
Summary

Cancer treatment has shifted from general chemotherapy to targeted therapies by understanding tumor growth mechanisms. This review highlights advances in targeted cancer therapy for epithelial cancers.

Keywords:
human geneticsindividualized medicinemolecular targeted therapymutationneoplasm

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