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Related Concept Videos

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Related Experiment Video

Updated: Apr 26, 2026

Semi-quantitative Assessment Using [18F]FDG Tracer in Patients with Severe Brain Injury
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"Brain on fire": a new imaging sign.

Prasanna Epaliyanage1, Andrew King2, Timothy Hampton3

  • 1Department of Neurosurgery, Hurstwood Park Neurological Centre, Lewes Road, Haywards Heath RH16 4EX, UK; Department of Neurosurgery, King's College Hospital NHS Foundation Trust, London, UK.

Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia
|July 22, 2014
PubMed
Summary

Primary central nervous system marginal zone B cell lymphoma is rare and typically dural-based. This case highlights an unusual, non-dural-based presentation of this lymphoma, expanding diagnostic considerations.

Keywords:
Central nervous systemImaging appearanceMarginal zone B cell lymphomaPrimary

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Area of Science:

  • Neuropathology
  • Neuroradiology
  • Oncology

Background:

  • Primary central nervous system (CNS) marginal zone B cell lymphoma is an uncommon lymphoid neoplasm.
  • It characteristically arises from dura mater, presenting as a dural-based mass.

Observation:

  • This report details a rare case of primary CNS marginal zone B cell lymphoma.
  • The tumor exhibited a non-dural-based location within the CNS.
  • The lesion presented with an atypical imaging morphology.

Findings:

  • The patient's lymphoma was confirmed as primary CNS marginal zone B cell lymphoma.
  • Imaging findings were unusual and not previously documented for this specific condition.
  • The non-dural-based presentation challenges typical diagnostic patterns.

Implications:

  • This case broadens the understanding of CNS marginal zone B cell lymphoma presentations.
  • It underscores the importance of considering atypical imaging features in CNS lymphoma diagnosis.
  • Further research may elucidate the diverse origins and imaging characteristics of CNS lymphomas.