Related Experiment Video

Updated: Apr 26, 2026

A Human Fallopian Tube Model for Investigation of C. trachomatis Infections
09:11

A Human Fallopian Tube Model for Investigation of C. trachomatis Infections

Published on: August 11, 2012

15.5K

Trachoma

Hugh R Taylor1, Matthew J Burton2, Danny Haddad3

  • 1Melbourne School of Population and Global Health, University of Melbourne, Carlton, VIC, Australia.

Lancet (London, England)
|July 22, 2014
PubMed

Insights

Trachoma, a leading infectious cause of blindness, is caused by Chlamydia trachomatis. The SAFE Strategy combats this disease through surgery, antibiotics, facial cleanliness, and environmental improvements.

Area of Science:

  • Ophthalmology
  • Infectious Diseases
  • Public Health

Background:

  • Trachoma is the leading infectious cause of preventable blindness globally.
  • Childhood Chlamydia trachomatis infections cause conjunctival inflammation and scarring, leading to trichiasis (inturned eyelashes).
  • Inadequate hygiene in resource-poor settings facilitates disease transmission.

Purpose of the Study:

  • To summarize the epidemiology, pathophysiology, and control of trachoma.
  • To highlight the effectiveness of the SAFE Strategy in trachoma elimination efforts.

Main Methods:

  • Review of epidemiological and pathophysiological data on trachoma.
  • Description of the integrated SAFE Strategy components: Surgery, Antibiotics, Facial cleanliness, Environmental improvement.

Main Results:

  • The SAFE Strategy has proven successful in eliminating trachoma in multiple countries.
  • Global initiatives are actively working towards the worldwide elimination of blinding trachoma.

Conclusions:

  • Integrated control programs utilizing the SAFE Strategy are effective in combating trachoma.
  • Continued global efforts are essential to achieve the goal of eliminating blinding trachoma by 2020.

More Related Videos

Surgical Correction for Pediatric Epiblepharon and Trichiasis03:59

Surgical Correction for Pediatric Epiblepharon and Trichiasis

Published on: July 8, 2025

848
Nasolacrimal Lavage as a Treatment for Ocular Surface Toxic Soup Syndrome03:40

Nasolacrimal Lavage as a Treatment for Ocular Surface Toxic Soup Syndrome

Published on: April 25, 2025

1.4K

Related Concept Videos

Sexually Transmitted Infections01:26

Sexually Transmitted Infections

Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
1.9K
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
5.1K
Bacterial Phylum Chlamydiae01:29

Bacterial Phylum Chlamydiae

The phylum Chlamydiae or Chlamydiota is composed of a single order, Chlamydiales. This phylum consists entirely of obligate intracellular parasites that infect eukaryotic hosts. While human pathogens within this group have been studied extensively, the phylum encompasses many species capable of interacting with various eukaryotic organisms. Members of Chlamydiae are typically small cocci, approximately 0.5 μm in diameter, and exhibit a distinctive developmental cycle. As is characteristic...
832
Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
1.7K
Trachea01:22

Trachea

The trachea, commonly known as the windpipe, is a vital part of the human respiratory system. It serves as a passageway for air to travel between the larynx and the bronchi, allowing oxygen to reach the lungs. Let's explore its anatomical features, dimensions, layers of the tracheal wall, associated muscles, and the functions of its parts.
Anatomical Features:
Location: About half of the trachea is situated in the neck, anterior to the esophagus, and extends from the larynx (at the level of...
6.2K
Microbiome of the Eye01:22

Microbiome of the Eye

The human eye has a specialized microbiota that reflects its unique anatomical and immunological environment. This low-biomass microbial community predominantly colonizes the conjunctiva and eyelid margins, playing a vital role in ocular surface homeostasis and defense. Despite its proximity to the richly colonized facial skin, the ocular surface maintains a distinct microbial profile due to continuous mechanical and biochemical defense mechanisms.The conjunctival surface hosts fewer microbial...
67