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Published on: November 11, 2022
Monoterpenoid coumarins from the peels of Clausena lansium
Hui-Dong Deng1, Wen-Li Mei1, Zhi-Kai Guo1
1Key Laboratory of Biology and Genetic Resources of Tropical Crops, Ministry of Agriculture (Hainan Key Laboratory for Research and Development of Natural Products from Li Folk Medicine), Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou, Hainan, P. R. China.
Abstract:
A phytochemical investigation on the peels of Clausena lansium (Lour.) Skeels led to the isolation of two new monoterpenoid coumarins, named clauslactone V (1) and clauslactone W (2), together with three known analogues (3-5). Their structures were elucidated by spectroscopic techniques (UV, IR, MS, 1D and 2D NMR). All the compounds were evaluated for hypoglycemic activity, and compounds 1-5 showed α-glucosidase inhibitory activity in vitro.
