Related Experiment Video
Updated: Apr 26, 2026
An In Vitro Approach to Photodynamic Therapy
Published on: August 17, 2018
Balanoposthitis with epithelial dysplasia treated by photodynamic therapy
Aleksandra Kawczyk-Krupka1, Aleksandra Ledwon, Justyna Malyszek
1Center for Laser Diagnostics and Therapy, Clinic of Internal Diseases and Physical Medicine, Silesian Medical University, 15 Batory St., PL-41902 Bytom, Poland.
Background:
Balanoposthitis is the inflammation of the glans and foreskin of the penis. Balanoposthitis is a risk factor of penis cancer. Photodynamic therapy using topical aminolaevulinic acid could be an alternative therapeutic approach in cases resistant to conventional treatment.
Objective:
We present the case of 50-year-old male with balanoposthitis associated with epithelial dysplasia treated by topical aminolaevulinic acid photodynamic therapy.
Methods:
On admission, 2hours after topical application of aminolaevulinic acid we performed the photodynamic diagnosis estimating pathological fluorescence of the lesions. Then 4 hours after topical application of aminolaevulinic acid we followed irradiation using light in the wavelength 630nm and giving a dose 120J/cm(2).
Results:
After 5 procedures of photodynamic therapy we noticed complete recovery.
Conclusion:
Photodynamic therapy appears to be an alternative, non-invasive, well tolerated method of treatment of eithelial dysplasia of the penis.
