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Updated: Jul 17, 2026

Establishment of a Primary Culture of Patient-derived Soft Tissue Sarcoma
Published on: April 11, 2018
Liposarcoma: a soft tissue tumor with many presentations
H J Mankin1, K P Mankin, D C Harmon
1Departments of Orthopaedics, Pathology, Radiation Oncology, Hematology/Oncology, Massachusetts General Hospital, Boston, MA, USA, HMANKIN@PARTNERS.ORG.
Abstract:
Liposarcoma is an uncommon connective tissue tumor arising from lipoblast cells. The lesion is located in body soft parts and rarely arises from the bones. The tumors are variable in presentation ranging from benign well-differentiated tumors to myxoid and round cell-dedifferentiated and pleomorphic forms which can present with metastases. The lesions are most often treated by surgical resection. Chemotherapy and radiation may be added to the treatment of the more malignant variants with some success.
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